Veröffentlichungen Bioressourcen


Titel/ Autor




A quantitative micro-tomographic gut atlas of the lepidopteran model insect Manduca sexta

Windfelder AG, Steinbart J, Flögel U, Scherberich J, Kampschulte M, Krombach GA, Vilcinskas A.




An Assassin’s Secret: Multifunctional Cytotoxic Compounds in the Predation Venom of the Assassin Bug Psytalla horrida (Reduviidae, Hemiptera)

Fischer ML, Fabian B, Pauchet Y, Wielsch N, Sachse S, Vilcinskas A, Vogel H.



Aristophania vespae gen. nov., sp. nov., isolated from wasps, is related to Bombella and Oecophyllibacter, isolated from bees and ants

Guzman J, Won M, Poehlein A, Sadat Sombolestani A, Mayorga-Ch D, Laureys D, De Clippeleer J, Kämpfer P, Daniel R, Vilcinskas A, Vandamme P, Kwon SW.

International Journal of Systematic and Evolutionary Microbiology



Crude Extracts of Talaromyces Strains (Ascomycota) Affect Honey Bee (Apis mellifera) Resistance to Chronic Bee Paralysis Virus

Vocadlova K, Lamp B, Benes K, Matha V, Lee KZ, Vilcinskas A.




Draft Genome Sequences of Algoriphagus sp. Strain PAP.12 and Roseivirga sp. Strain PAP.19, Isolated from Marine Samples from Papua, Indonesia

Riyanti, Zumkeller CM, Spohn M, Mihajlovic S, Schwengers O, Goesmann A, Choironi NA, Schäberle TF, Harwoko H

Microbiology Resource Announcements 



Draft Genome Sequence of Sinomicrobium sp. Strain PAP.21, Isolated from a Coast Sample of Papua, Indonesia

Riyanti, Zumkeller CM, Spohn M, Mihajlovic S, Schwengers O, Goesmann A, Riviani R, Meinita MDN, Schäberle TF, Harwoko H

Microbiology Resource Announcements



Full Profiling of GE81112A, an Underexplored Tetrapeptide Antibiotic with Activity Against Gram-Negative Pathogens

Schuler SMM, Jürjens G, Marker A, Hemmann U, Rey A, Yvon S, Lagrevol M, Hamiti M, Nguyen F, Hirsch R, Pöverlein C, Vilcinskas A, Hammann P, Wilson DN, Mourez M, Coyne S, Bauer A.

Microbiology Spectrum


Functional Profiling of the A-Family of Venom Peptides from the Wolf Spider Lycosa shansia

Lüddecke T, Dersch L, Schulte L, Hurka S, Paas A, Oberpaul M, Eichberg J, Hardes K, Klimpel S, Vilcinskas A.




Human-induced salinity changes impact marine organisms and ecosystems

Röthig T, Trevathan-Tackett SM, Voolstra CR, Ross C, Chaffron S, Durack PJ, Warmuth LM, Sweet M. 

Global Change Biology

Human-induced salinity changes impact marine organisms and ecosystems – PubMed (


Insect feed in sustainable crustacean aquaculture

Röthig T, Barth A, Tschirner M, Schubert P, Wenning M, Billion A, Wilke T, Vilcinskas A.

Journal of Insects as Food and Feed


Metabolic engineering of the shikimate pathway in Amycolatopsis strains for optimized glycopeptide antibiotic production

Goldfinger V, Spohn M, Rodler JP, Sigle M, Kulik A, Cryle MJ, Rapp J, Link H, Wohlleben W, Stegmann E.

Metabolic Engineering

Metabolic engineering of the shikimate pathway in Amycolatopsis strains for optimized glycopeptide antibiotic production - PubMed (


Peptidomics as a Tool to Assess the Cleavage of Wine Haze Proteins by Peptidases from Drosophila suzukii Larvae

Albuquerque W, Ghezellou P, Lee KZ, Schneider Q, Gross P, Kessel T, Omokungbe B, Spengler B, Vilcinskas A, Zorn H, Gand M.



Potato (Solanum tuberosum) as a New Host for Pentastiridius leporinus (Hemiptera: Cixiidae) and Candidatus Arsenophonus Phytopathogenicus

Behrmann SC, Rinklef A, Lang C, Vilcinskas A, Lee KZ.



RNA interference to combat the Asian tiger mosquito in Europe: A pathway from design of an innovative vector control tool to its application

Müller R, Bálint M, Hardes K, Hollert H, Klimpel S, Knorr E, Kochmann J, Lee KZ, Mehring M, Pauls SU, Smets G, Steinbrink A, Vilcinskas A.

Biotechnology Advances


Spatial metabolomics reveal divergent cardenolide processing in the monarch (Danaus plexippus) and the common crow butterfly (Euploea core)

Dreisbach D, Bhandari DR, Betz A, Tenbusch L, Vilcinskas A, Spengler N, Petschenka G.

Molecular Ecology Resources


Vagococcus luciliae sp. nov., isolated from the common green bottle fly Lucilia sericata

Guzman J, Poehlein A, Daniel R, Kämpfer P, Vilcinskas A.

International Journal of Systematic and Evolutionary Microbiology


Venom biotechnology: casting light on nature’s deadliest weapons using synthetic biology

Lüddecke T, Paas A, Harris RJ, Talmann L, Kirchhoff KN, Billion A, Hardes K, Steinbrink A, Gerlach D, Fry BG, Vilcinskas A.

Frontiers in bioengineering and biotechnology


You are what you eat—ecological niche and microhabitat influence venom activity and composition in aquatic bugs

Fischer ML, Yepes Vivas SA, Wielsch N, Kirsch R, Vilcinskas A, Vogel H.

Proceedings of the Royal Society B


Titel/ Autor



Agromyces archimandritae sp. nov., isolated from the cockroach Archimandrita tessellata

Guzman J, Ortúzar M, Poehlein A, Daniel R, Trujillo ME, Vilcinskas A. 

International journal of systematic and evolutionary microbiology 72:005283

DOI: 10.1099/ijsem.0.005283 


An engineered protein-based submicromolar competitive inhibitor of the Staphylococcus aureus virulence factor aureolysin

Mendes SR, Eckhard U, Rodríguez-Banqueri A, Guevara T, Czermak P, Marcos E, Vilcinskas A, Gomis-Rüth FX.

Computational and Structural Biotechnology Journal 20, 534–544.

DOI: 10.1016/j.csbj.2022.01.001


Antidiabetic Profiling of Veramycins, Polyketides Accessible by Biosynthesis, Chemical Synthesis, and Precursor-Directed Modification

Dardić D, Böhringer N, Plaza A, Zubeil F, Pohl J, Sommer S, Padva L, Becker J, Patras MA, Bill M, Kurz M, Toti L, Görgens SW, Schuler SMM, Billion A, Schwengers O, Wohlfart P, Goesmann A, Tennagels N, Vilcinskas A, Hammann PE, Schäberle TF, Bauer A.

Org Chem Front

DOI: 10.1039/D1QO01652K


Antimicrobial, Insecticidal and Cytotoxic Activity of Linear Venom Peptides from the Pseudoscorpion Chelifer cancroides

Krämer J, Lüddecke T, Marner M, Maiworm E, Eichberg J, Hardes K, Schäberle TF, Vilcinskas A, Predel R.

Toxins 14, 58.

DOI: 10.3390/toxins1401005


Antiviral Potential of Natural Resources against Influenza Infections. 

Eichberg J, Maiworm E, Oberpaul M, Czudai-Matwich V, Lüddecke T, Vilcinskas A,  Hardes K.

Viruses 14, 2452.

DOI: 10.3390/v14112452


Bioactive Natural Products from Bacteroidetes 

Brinkmann S, Spohn MS, Schäberle TF.

Nat. Prod. Rep., 39, 1045-1065

DOI: 10.1039/D1NP00072A


Bioactivity Profiling of In Silico Predicted Linear Toxins from the Ants Myrmica rubra and Myrmica ruginodis

Hurka S,  Lüddecke T, Paas A, Dersch L, Schulte L, Eichberg J, Hardes K,  Brinkrolf K,  Vilcinskas A.

Toxins 14(12), 846.

DOI: 10.3390/toxins14120846


Biology and rearing of the planthopper Pentastiridius leporinus, an emerging pest in sugar beets.

Behrmann S, Witczak N, Lang C,  Schieler M,  Dettweiler A, Kleinhenz B,  Schwind M, Vilcinskas A, Lee KZ.

Insects 13, 656.

DOI: 10.3390/insects13070656


Combination of high-throughput microfluidics and FACS technologies to leverage the numbers game in natural product discovery 

Oberpaul M, Brinkmann S, Marner M, Mihajlovic S, Leis B , Patras MA, Hartwig C, Vilcinskas A, Hammann PE , Schäberle TF, Spohn M, Glaeser J.

Microbial Biotechnology 15(2):415-430

DOI: 10.1111/1751-7915.13872


Diet fermentation leads to microbial adaptation in black soldier fly (Hermetia illucens) larvae reared on palm oil side streams. 

Klueber P,  Tegtmeier D, Hurka S, Pfeiffer J, Vilcinskas A, Rühl M, Zorn H.

Sustainability 14, 5626.

DOI: 10.3390/su14095626


Discovery of Marine Natural Products as Promising Antibiotics against Pseudomonas aeruginosa

Li H, Maimaitiming M, Zhou Y, Li H, Wang P, Liu Y, Schäberle TF, Liu Z, Wang C-Y.

Mar Drugs 4;20(3):192

DOI: 10.3390/md20030192


Genome analysis suggests the bacterial family Acetobacteraceae is a source of undiscovered specialized metabolites

Guzman J, Vilcinskas A.

Antonie Van Leeuwenhoek-International Journal of General and Molecular Microbiology 115(1), 41-58

DOI: 10.1007/s10482-021-01676-7


Genome Mining-Guided Discovery and Characterization of the PKS-NRPS-Hybrid Polyoxyperuin produced by a Marine-Derived Streptomycete. 

Kresna ID, Wuisan Z, Pohl JM, Mettal U,  Linares Otoya V, Gand M, Marner M, Linares Otoya L, Böhringer N, Vilcinskas A, Schäberle T. 

Journal of Natural Products, 85(4):888-898 

DOI: 10.1021/acs.jnatprod.1c01018 


Genomic and Chemical Decryption of the Bacteroidetes Phylum for Its Potential to Biosynthesize Natural Products

Brinkmann S,  Kurz M, Patras MA, Hartwig C, Marner M, Leis B, Billion A, Kleiner Y, Bauer A, Toti L, Pöverlein C, Hammann PE, Vilcinskas A, Glaeser J, Spohn M, Schäberle TF.

Antimicrobial Chemotherapy 10 (3)

DOI: 10.1128/spectrum.02479-21


Genome Mining-Guided Discovery and Characterization of the PKS-NRPS-Hybrid Polyoxyperuin produced by a Marine-Derived Streptomycete 

Kresna ID, Wuisan ZG, Pohl JM, Mettal U, Linares-Otoya V, Gand M, Marner M, Linares-Otoya L, Böhringer N, Vilcinskas A, Schäberle TF.

J Nat Prod

DOI: 10.1021/acs.jnatprod.1c01018


Heilen mit Tiergiften: Tödliche Waffen des Tierreichs zur Therapie von Krankheiten nutzbar machen

Lüddecke T, Vilcinskas A.

Chemie in unserer Zeit 56(2), 86-91. 

DOI: 10.1002/ciuz.202100005


High-throughput screening of caterpillars as a platform to study host–microbe interactions and enteric immunity

Windfelder AG, Müller FHH, Mc Larney B, Hentschel M, Böhringer AC, von Bredow CR, Leinberger FH, Kampschulte M, Maier L, von Bredow YM, Flocke V, Merzendorfer H, Krombach GA, Vilcinskas A, Grimm J, Trenczek TE, Flögel U.

Nature Communications 

DOI: 10.1038/s41467


Identification, Characterization, and Synthesis of Natural Parasitic Cysteine Protease Inhibitors: Pentacitidins Are More Potent Falcitidin Analogues

Brinkmann S, Semmler S, Kersten C, Patras MA, Kurz M, Fuchs N, Hammerschmidt SJ, Legac J, Hammann PE, Vilcinskas A, Rosenthal PJ, Schirmeister T, Bauer A, Schäberle TF.

ACS Chem Biol 17, 576-589

DOI: 10.1021/acschembio.1c00861


Identification of volatile producing enzymes in higher fungi: Combining analytical and bioinformatic methods

Orban AM, Rühl M.

Chemical microbiology. Part A

DOI: 10.1016/bs.mie.2021.12.007


Insect models in nutrition research

Tonk-Rügen M, Vilcinskas A, Wagner A.

Biomolecules, 12, 1668

DOI: 10.3390/biom12111668


In vitro biological activity of extracts from marine bacteria cultures against Toxoplasma gondii and Mycobacterium tuberculosis

Quintero M, Blandon LM, Vidal OM, Guzman JD, Gomez-Marin JE, Patino AD, Molina DA, Puerto-Castro GM, Gomez-Leon J.

Journal of applied microbiology 10(1) 1 e01664-21

DOI: 10.1111/jam.15397


Isolation, characterization, and bioactivity profiling of oxazoline containing madurastatin siderophores from Actinomadura sp

Bill MK, Kleiner Y, Flügel J, Kurz M, Spohn M, Marner M, Mihajlovic S, Vilcinskas A, Schäberle T, Hammann P, Patras M, Schuler S.

Journal of Antibiotics 75(10), 576-582.

DOI: 10.1038/s41429-022-00557-z


Isolation of Bacterial and Fungal Microbiota Associated with Hermetia illucens Larvae Reveals Novel Insights into Entomopathogenicity

Klüber P, Müller S, Schmidt J, Zorn H, Rühl M.


DOI: 10.3390/microorganisms10020319


Isolation of Hermetia illucens larvae core gut microbiota by two different cultivation strategies

Cifuentes Y, Vilcinskas A, Kämpfer P, Glaeser S.

Antonie Van Leeuwenhoek-International Journal of General and Molecular Microbiology 115 (6), 821-837.

DOI: 10.1007/s10482-022-01735-7


Matrix metalloproteinases and their inhibitors - pleiotropic functions in insect immunity and metamorphosis

Vilcinskas A.

FEBS journal 289, 2805–2808

DOI: 10.1111/febs.16314


Modern venomics – Current insights, novel methods and future perspectives in biological and applied animal venom research

Von Reumont BM,  Anderluh G,  Antunes A, Ayvazyan N, Beis D, Caliskan F,  Crnkovic A, Damm M, Dutertre S, Ellgaard L , Gajski G, German H, Halassy B,  Hempel BF, Hucho T, Igci N,  Ikonomopoulou MP, Karbat I,  Klapa MI, Koludarov I, Kool J, Lüddecke T, Mansour RB, Modica MV, Moran Y, Nalbantsoy A, Pachon Ibanez ME, Panagiotopolous A, Reuveny E, Sanchez Cespedes J, Sombke A, Surm JM, Undheim EAB, Verdes A, Zancolli G.

Gigascience 11, giac048.

DOI: 10.1093/gigascience/giac048 


Pathogenicity of La Jolla virus in Drosophila suzukii following oral administration

Linscheid Y, Kessel T, Vilcinskas A, Lee KZ.

Viruses 14, 2158.

DOI: 10.3390/v14102158


Production of an Anise- and Woodruff-like Aroma by Monokaryotic Strains of Pleurotus sapidus Grown on Citrus Side Streams

Bürger F, Koch M, Fraatz MA, Omarini AB, Berger RG, Zorn H.


DOI: 10.3390/molecules27030651


Pseudocitrobacter corydidari sp. nov., isolated from the Asian emerald cockroach Corydidarum magnifica

Guzman J, Poehlein A, Glaeser S, Schwengers O, Blom J, Hollensteiner J, Kaempfer P, Vilcinskas A.

International Journal of Systematic and Evolutionary Microbiology 27(8)



Quantification methods for viruses and virus-like particles applied in biopharmaceutical production processes

Lothert K, Eilts F, Wolff M.

Expert review of vaccines

DOI: 10.1080/14760584.2022.2072302


Replacement of Pregastric Lipases in Cheese Production: Identification and Heterologous Expression of a Lipase from Pleurotus citrinopileatus

Sowa MA, Kreuter N, Sella N, Albuquerque W, Manhard J, Siegl A, Ghezellou P, Li B, Spengler B, Weichhard E, Rühl M, Zorn H, Gand M.

ACS Publications

DOI: 10.1021/acs.jafc.1c07160


SARS-CoV-2 and West Nile virus prevalence studies in racoons and racoon dogs in Germany. 

Keller M, Peter N, Holicki C, Schanz A, Ziegler U, Eiden M, Dörge D, Vilcinskas A, Groschup M, Klimpel S. 

Viruses, 14, 2559

DOI: 10.3390/v14112559


Sequestration of Defenses against Predators Drives Specialized Host Plant Associations in Preadapted Milkweed Bugs (Heteroptera: Lygaeinae)

Petschenka G, Halitschke R, Züst T, Roth A, Stiehler S, Tenbusch L, Hartwig C, Moreno Gámez JF, Trusch R, Deckert J, Chalušová K, Vilcinskas A, Exnerová A.


DOI: 10.1086/719196


Stingray venom proteins: Mechanisms of action revealed using a novel network pharmacology approach

Kirchhoff KN, Billion A, Voolstra CR, Kremb S, Wilke T, Vilcinskas, A.

Marine Drugs 20, 27

DOI: 10.3390/md20010027


The Discovery and Structure-Activity Evaluation of (+)-Floyocidin B and Synthetic Analogs

Kleiner Y, Pöverlein C, Klädtke J, Kurz M, König HF, Becker J, Mihajlovic S, Zubeil F, Marner M, Vilcinskas A, Schäberle TF, Hammann P, Schuler SMM, Bauer A.


DOI: 10.1002/cmdc.202100644


The Pharmacological Potential of Novel Melittin Variants from Honeybee and Solitary Bees in the Context of Inflammation and Cancer

Erkoc P, von Reumont BM, Lüddecke T, Henke M, Ulshöfer T, Vilcinskas A, Fürst R, Schiffmann S.

Toxins 14(12), 818

DOI: 10.3390/toxins14120818


The biology and evolution of spider venoms

Lüddecke T, Herzig V, Reumont BM von, Vilcinskas A.

Biological reviews 7, 163–178. 163

DOI: 10.1111/brv.12793


Three new andrastin derivatives from the endophytic fungus Penicillium vulpinum

Qin YY, Huang XS, Liu XB, Mo TX, Xu ZL, Li BC, Qin XY, Li J, Schäberle TF, Yang RY.

Natural product research

DOI: 10.1080/14786419.2020.1853725


Trichoderma-Derived Pentapeptides from the Infected Nest Mycobiome of the Subterranean Termite Coptotermes testaceus

Oberpaul M, Spohn M, Brinkmann S, Mihajlovic S, Marner M, Patras MA, Toti L, Kurz M, Hammann PE, Vilcinskas A, Glaeser J, Schäberle TF.

Chembiochem, 23 (10), e202100698  

DOI: 10.1002/cbic.202100698


Venomics of the Central European Myrmicine Ants Myrmica rubra and Myrmica ruginodis. 

Hurka S, Brinkrolf K, Özbek R, Förster F, Billion A, Heep J, Timm T, Lochnit G,  Vilcinskas A, Lüddecke T.

Toxins 14(5): 358.

DOI: 10.3390/toxins14050358

Albuquerque W, Ghezellou P, Li B, Spengler B, Will F, Zorn H, Gand M. Identification of intact peptides by top-down peptidomics reveals cleavage spots in thermolabile wine proteins (2021) Food Chem, 363, 130437. DOI: 10.1016/j.foodchem.2021.130437

Ali A, Ellinger B, Brandt SC, Betzel C, Rühl M, Wrenger C, Schlüter H, Schäfer W, Brognaro H, Gand M. Genome and Secretome Analysis of Staphylotrichum longicolleum DSM105789 Cultured on Agro-Residual and Chitinous Biomass (2021) Microorganisms 2021, 9(8), 1581. DOI:10.3390/microorganisms9081581

Bartling M, Thümecke S, Vilcinskas A, Lee KZ. Exposure to low doses of pesticides induces an immune response and the production of nitric oxide in honeybees (2021) Scientific Reports, 11(1), 6819. DOI: 10.1038/s41598-021-86293-0.

Baudach A, Vilcinskas A. The European map butterfly Araschnia levana as a model to study the molecular basis and evolutionary ecology of seasonal polyphenism (2021) Insects 12, 325. DOI: 10.3390/insects12040325

Berger A, Petschenka G, Degenkolb T, Geisthardt M, Vilcinskas A. Insect Collections as an Untapped Source of Bioactive Compounds—Fireflies (Coleoptera: Lampyridae) and Cardiotonic Steroids as a Proof of Concept (2021) Insects 2021, 12, 689. DOI: 10.3390/insects12080689

Bertrams W, Lindhauer NS, Rieke MC, Paas A, Hoffmann K, Greene B, Visekruna A, Vilcinskas A, Seidel K, Schmeck B. Tribolium castaneum defensin 1 selectively kills Moraxella catarrhalis in an in vitro infection model but does not impair harm commensal bacteria (2021) Virulence 12(1), 1003-101. DOI: 10.1080/21505594.2021.1908741

Bill M-K, Brinkmann S, Oberpaul M, Patras MA, Leis B, Marner M, Maitre MP, Hammann PE, Vilcinskas A, Schuler SMM, Schäberle TF. Novel Glycerophospholipid, Lipo- and N-acyl Amino Acids from Bacteroidetes: Isolation, Structure Elucidation and Bioactivity (2021) Molecules 2021, 26 (17). DOI: 10.3390/molecules26175195

Birrenbach O, Faust F, Ebrahimi M, Fan R, Czermak P. Recovery and Purification of Protein Aggregates from Cell Lysates using Ceramic Membranes: Fouling Analysis and Modeling of Ultrafiltration, Frontiers in Chemical Engineering (2021) Frontiers in Chemical Engineering section Separation Processes 15, 3, 656345 DOI: 10.3389/fceng.2021.656345

Birk F, Brescia FF, Fraatz MA, Pelzer R, Zorn H. Aroma active alkylated pyrazines are produced by Basfia succiniciproducens as by-products of succinic acid production (2021) Flavour and Fragrance Journal, 36 (5), 605-612. DOI: 0.1002/ffj.3674

Böhringer N, Green R, Liu Y, Mettal U, Marner M, Modaresi SM, Jakob RP, Wuisan ZG, Maier T, Iinishi A, Hiller S, Lewis K, Schäberle TF. Mutasynthetic production and antimicrobial characterisation of Darobactin analogs. (2021) Microbiol Spectr, 2021, 9, Issue 3, e01535-21. DOI: 10.1128/spectrum.01535-21

Böhringer N, Patras MA, Schäberle TF. Heterologous Expression of Pseudouridimycin and Description of the Corresponding Minimal Biosynthetic Gene Cluster (2021) Molecules 2021, 26 (2). DOI: 10.3390/molecules26020510

Brandt SC, Brognaro H, Ali A. et al. Insights into the genome and secretome of Fusarium metavorans DSM105788 by cultivation on agro-residual biomass and synthetic nutrient sources (2021) Biotechnol Biofuels 14(74), 22. DOI: 10.1186/s13068-021-01927-9

Brescia FF, Pitelas W, Yalman S, Popa F, Hausmann HG, Wende RC, Fraatz MA, Zorn H. Formation of diastereomeric dihydromenthofurolactones by Cystostereum murrayi and aroma dilution analysis (ADA) based on dynamic headspace extraction (2021) J Agric Food Chem. DOI: 10.1021/acs.jafc.1c01478

Brinkmann S, Oberpaul M, Glaeser J, Schäberle TF. Two-step generation of monodisperse agarose-solidified double emulsions (w/w/o) excluding an inner oil barrier. (2021) MethodsX, 2021, 8, 101565, DOI: 10.1016/j.mex.2021.101565

Brinkrolf K, Shukla SP, Griep S. et al. Genomic analysis of novel Yarrowia-like yeast symbionts associated with the carrion-feeding burying beetle Nicrophorus vespilloides (2021) BMC Genomics 22, 323. DOI: 10.1186/s12864-021-07597-z

Burian A, Pinn D, Peralta-Maraver I, Sweet M, Mauvisseau Q, Eyice O, Bulling M, Röthig T, Kratina P. Predation increases multiple components of microbial diversity in activated sludge communities (2021) The ISME Journal DOI: 10.1038/s41396-021-01145-z

Carrau T, Lamp B, Reuscher C, Vilcinsksas A, Lee K-Z. Organization of the structural protein region of La Jolla virus Isolated from the invasive pest insect Drosophila suzukii(2021) Viruses 13, 740. DOI: 10.3390/v13050740

Carrau T, Thümecke S, Silva LMR, Perez-Bravo D, Gärtner U, Taubert A, Hermosilla C, Vilcinskas A, Lee KZ. The Cellular Innate Immune Response of the Invasive Pest Insect Drosophila suzukii against Pseudomonas entomophila Involves the Release of Extracellular Traps (2021) Cells 10(12):3320 DOI: 10.3390/cells10123320

Edelmann D, Leinberger FH, Schmid NE, Oberpaul M, Schäberle TF, Berghoff BA. Elevated Expression of Toxin TisB Protects Persister Cells against Ciprofloxacin but Enhances Susceptibility to Mitomycin C (2021) Microorganisms 2021, 9(5), 943. DOI: 10.3390/microorganisms9050943

Edelmann D, Oberpaul M, Schäberle TF, Berghoff BA. Post-transcriptional deregulation of the tisB/istR-1 toxin–antitoxin system promotes SOS-independent persister formation in Escherichia coli (2021) Environmental microbiology reports, 13(2), 159-168. DOI: 10.1111/1758-2229.12919

Fan R, Burghardt JP, Huang JQ, Xiong T, Czermak P. Purification of crude fructo-oligosaccharide preparations using probiotic bacteria for the selective fermentation of monosaccharide byproducts (2021) Frontiers in Microbiology, DOI: 10.3389/fmicb.2020.620626

Fan R, Burghardt JP, Czermak P. Process Design Fundamentals for the Production of Prebiotic Oligosaccharides using Membrane Integrated Reactor Systems (2021) Chemie Ingenieur Technik 93, 1-2, 306-310 DOI: 10.1002/cite.202000127

Fan R, Dresler J, Tissen D, Wen L, Czermak P. In situ purification and enrichment of fructo-oligosaccharides by fermentation with probiotic Bacillus coagulans and selective catalysis using immobilized fructosyltransferase (2021) Bioresource Technology 342, 125969 DOI: 10.1016/j.biortech.2021.125969

Gegner J, Vogel H, Billion A, Förster F, Vilcinskas A. Complete Metamorphosis in Manduca sexta Involves Specific Changes in DNA Methylation Patterns (2021) Front. Ecol. Evol. 9:646281. DOI: 10.3389/fevo.2021.646281

Guzman J, Sombolestani A, Poehlein A, Daniel R, Cleenwerck I, Vandamme P, Vilcinskas A. Entomobacter blattae gen. nov., sp. nov. – a new member of the Aceto-bacteraceae isolated from the gut of the cockroach Gromphadorhina portentosa (2021) International Journal of Systematic and Evolutionary Microbiology 71(3). DOI: 10.1099/ijsem.0.004666

Guzman J, Vilcinskas A. Draft Genome Sequence of Rhodococcus rhodochrous Strain G38GP, Isolated from the Madagascar Hissing Cockroach (2021) Epub Oct 7;10(40):e0077721 DOI: 10.1128/MRA.00777-21

Guzman J, Vilcinskas A. Genome analysis suggests the bacterial family Acetobacteraceae is a source of undiscovered specialized metabolites. (2021) Antonie Van Leeuwenhoek. Epub 2021 Nov 10. PMID: 34761294 DOI: 10.1007/s10482-021-01676-7

Hammer AK, Emrich NO, Ott J, Birk F, Fraatz MA, Ley JP, Geissler T, Bornscheuer UT, Zorn H. Biotechnological production and sensory evaluation of ω1-unsaturated aldehydes (2021) J Agric Food Chem 69:345–353. DOI: 10.1021/acs.jafc.0c06872

Jiso A, Demuth P, Bachowsky M, Haas M, Seiwert N, Heylmann D, Rasenberger B, Christmann M, Dietrich L, Brunner T, Riyanti R, Schäberle TF, Plubrukarn A, Fahrer J. Natural Merosesquiterpenes Activate the DNA Damage Response via DNA Strand Break Formation and Trigger Apoptotic Cell Death in p53-Wild-Type and Mutant Colorectal Cancer (2021) Cancers 2021, 13, 3282. DOI: 10.3390/cancers13133282

Kaderka R, Ferretti N, Hüsser M, Lüddecke T, West R. Antikuna, a new genus with seven new species from Peru (Araneae: Theraphosidae: Theraphosinae) and the highest altitude record for the family (2021) Journal of natural history 55, 21-22, 1335-140. DOI: 10.1080/00222933.2021.1936680

Karrer D, Gand M, Rühl M. Engineering a lipoxygenase from cyclocybe aegerita towards long chain polyunsaturated fatty acids (2021) AMB Expr, 11(37), 7. (2021). DOI: 10.1186/s13568-021-01195-8

Karrer D, Gand M, Rühl, M. Expanding the Biocatalytic Toolbox with a New Type of ene/yne-Reductase from Cyclocybe aegerita (2021) ChemCatChem, 13(9), 2191-2199. DOI: 10.1002/cctc.202002011

Karrer D, Weigel V, Hoberg N. et al. Biotransformation of [U-13C]linoleic acid suggests two independent ketonic- and aldehydic cycles within C8-oxylipin biosynthesis in Cyclocybe aegerita (V. Brig.) Vizzini (2021) Mycol Progress, 20, 929–940. DOI: 10.1007/s11557-021-01719-3

Kirchhoff KN, Billion A, Voolstra CR, Kremb S, Wilke T, Vilcinskas A. Stingray Venom Proteins: Mechanisms of Action Revealed Using a Novel Network Pharmacology Approach. (2021) Mar Drugs 20(1):27 DOI: 10.3390/md20010027

Kleiner Y, Pöverlein C, Klädtke J, Kurz M, König H, Becker J, Mihajlovic S, Zubeil F, Marner M, Vilcinskas A, Schäberle TF, Hammann PE, Schuler SMM, Bauer A. Evaluation of the Floyocidin scaffold as an anti-tuberculosis hit series. (2021) ChemMedChem, DOI: 10.1002/cmdc.202100644

Knorr E, Billion A, Fishilevich E, Tenbusch L, Frey MLF, Rangasamy M, Gandra P, Arora K, Lo W,  Geng C, Vilcinskas A, Narva KE. Knockdown of Genes Involved in Transcription and Splicing Reveals Novel RNAi Targets for Pest Control (2021) Front. Agron. 03 September 2021 DOI: 10.3389/fagro.2021.715823

Krahe N-K, Berger RG, Witt M, Zorn H, Omarini AB, Ersoy F. Monokaryotic Pleurotus sapidus strains with intraspecific variability of an alkene cleaving DyP-type peroxidase activity as a result of gene mutation and differential gene expression (2021)  Int J Mol Sci 22:1363; DOI: 10.3390/ijms22031363

Kresna IDM, Linares-Otoya L, Milzarek T, Duell ER, Mir Mohseni M, Mettal U, König GM, Gulder TAM, Schäberle TF. In vitro characterization of 3-chloro-4-hydroxybenzoic acid building block formation in ambigol biosynthesis (2021) Organic & biomolecular chemistry, 10, 2302-2311. DOI: 10.1039/D0OB02372H

Kruppa O, Gerlach D, Fan R, Czermak P. Development of a chemically defined medium for Planctopirus limnophila to increase biomass production (2021) Electronic Journal of Biotechnology 54, 86-93 DOI: 10.1016/j.ejbt.2021.09.002  

Leannec-Rialland V, Cabezas-Cruz A, Atanasova V, Chereau S, Ponts N, Tonk M, Vilcinskas A, Ferrer N, Valdés J, Richard-Forget F. Tick defensin γ‑core reduces Fusarium graminearum growth and abrogates mycotoxins production with high efficiency (2021) Scientific Reports 11:7962. DOI: 10.1038/s41598-021-86904-w

Lüddecke T, Herzig V, von Reumont BM, Vilcinskas A. The biology and evolution of spider venoms (2021) Biol. Rev. DOI: 10.1111/brv.12793

Lüddecke T, Paas A, Talmann L, Kirchhoff KN, von Reumont BM, Billion A, Timm T, Lochnit G, Vilcinskas A. A Spider Toxin Exemplifies the Promises and Pitfalls of Cell-Free Protein Production for Venom Biodiscovery (2021) Toxins 2021, 13, 575. DOI: 10.3390/toxins13080575

Lüddecke T, Vilcinskas A. Heilen mit Tiergiften: Tödliche Waffen des Tierreichs zur Therapie von Krankheiten nutzbar machen (2021) Chemie in unserer Zeit 55(6), DOI: 10.1002/ciuz.202100005

Maguire N, Ebrahimi M, Fan R, Gießelmann S, Ehlen F, Schütz S, Czermak P. Influence of Ceramic Membrane Surface Characteristics on the Flux Behavior of a Complex Fermentation Broth (2021) Membranes 11, 402 DOI: 10.3390/membranes11060402

Maheshwari G, Gessner DK, Neuhaus K, Most E, Zorn H, Eder K, Ringseis R. Influence of a biotechnologically produced oyster mushroom (Pleurotus sajor-caju) on the gut microbiota and microbial metabolites in obese Zucker rats (2021) Int. J. Mol. Sci.  69:1524–1535. DOI: 10.3390/ijms22105241

Maheshwari G, Wen G, Gessner DK, Ringseis R, Lochnit G, Eder K, Zorn H, Timm T. Tandem mass tag-based proteomics for studying the effects of a biotechnologically produced oyster mushroom against hepatic steatosis in obese Zucker rats (2021) J Proteomics, 242, 104255. DOI: 10.1016/j.jprot.2021.104255

Marschall MJM, Ringseis R, Gessner DK, Grundmann S, Most E, Maheshwari G, Zorn H, Eder K. Effect of ecdysterone on the hepatic transcriptome and lipid metabolism in lean and obese Zucker rats (2021) Int J Mol Sci; 22:5241; DOI: 10.3390/ijms22105241

Mo T-X, Huang X-S, Zhang W-X, Schäberle TF, Qin J-K, Zhou D-X, Qin X-Y, Xu Z-L, Li J, Yang R-Y. A series of meroterpenoids with rearranged skeletons from an endophytic fungus Penicillium sp. GDGJ-285 (2021) Organic chemistry frontiers, 8 (10), 2232-2241. DOI: 10.1039/D1QO00173F

Martin, S., P. Lesny, H. Glenner, J. Hecht, A. Vilcinskas, T. Bartolomaeus & L. Podsiadlowski. Genomic adaptations to an endoparasitic lifestyle in the morphologically atypical crustacean Sacculina carcini (Cirripedia: Rhizocephala) (2021). Genome Biology and Evolution 14(10)

Oberpaul M, Brinkmann S, Marner M, Mihajlovic S, Leis B, Patras MA, Hartwig C, Vilcinskas A, Hammann PE, Schäberle TF, Spohn M, Glaeser J. Combination of high-throughput microfluidics and FACS technologies to leverage the numbers game in natural product discovery (2021) Microbial Biotechnology 2021. DOI: 10.1111/1751-7915.13872

Oestreich A, Suli MI, Gerlach D, Fan R, Czermak P. Media development and process parameter optimization using statistical experimental designs for the production of nonribosomal peptides in Escherichia coli (2021) Electronic Journal of Biotechnology 52, 85-92 DOI: 10.1016/j.ejbt.2021.05.001

Oestreich AM, Reinhardt S, Gerlach D, Fan R, Czermak P. Isolation and purification of a hydrophobic nonribosomal peptide from Escherichia coli fermentation broth (2021) Separations 8, 241 DOI: 10.3390/separations8120241

Orban A, Weber A, Herzog R et al. Transcriptome of different fruiting stages in the cultivated mushroom Cyclocybe aegerita suggests a complex regulation of fruiting and reveals enzymes putatively involved in fungal oxylipin biosynthesis (2021) BMC Genomics, 22 (324), 23. DOI: 10.1186/s12864-021-07648-5

Rancilhac L, Irisarri I, Angelini C, Arntzen JW, Batik W, Bossuyt F, Künzel S, Lüddecke T, Pasmans F, Sanchez E, Weisrock D, Veith M, Wielstra B, Steinhart S, Hofreiter M, Vences M. Phylotranscriptomic evidence for pervasive ancient hybridisation among Old world salamanders (2021) Molecular Phylogenetics and Evolution, 155 (106967), DOI: 10.1016/j.ympev.2020.106967

Röthig T, Puntin P, Wong JCY, Burian A, McLeod W, Baker DM. Holobiont nitrogen control and its potential for eutrophication resistance in an obligate photosymbiotic jellyfish (2021) Microbiome, 9, 127, DOI: 10.1186/s40168-021-01075-0

Rügen N, Jenkins TP, Wielsch N, Vogel H, Hempel B-F, Süssmuth RD, Ainsworth S, Cabezas-Cruz A, Vilcinskas A, Tonk M. Hexapod Assassins’ Potion: Venom Composition and Bioactivity from the Eurasian Assassin Bug Rhynocoris iracundus (2021) Biomedicines 2021, 9, 819. DOI: 10.3390/biomedicines9070819

Schmidtberg H, von Reumont B, Lemke S, Vilcinskas A, Lüddecke T. Morphological analysis reveals a compartmentalized duct in the venom apparatus of the wasp spider (Argiope bruennichi) (2021) Toxins, 13, 270. DOI: 10.3390/toxins13040270

Schott M, Sandmann M, Cresswell J, Becher M, Eichner G, Brandt D, Halitschke D, Krueger S, Morlock G, Düring R-A, Vilcinskas A, Meixner M, Büchler R, Brandt A. Honeybee colonies compensate for pesticide-induced effects on royal jelly composition and brood survival with increased brood production (2021) Scientific Reports 11(1):62. DOI: 10.1038/s41598-020-79660-w.

Schwabe M, Griep S, Schmidtberg H, Plarre R, Goesmann A, Vilcinskas A, Vogel, H., Brinkrolf, K. Next-Generation Sequencing Analysis of the Tineola bisselliella Larval Gut Transcriptome Reveals Candidate Enzymes for Keratin Digestion (2021) Genes 202112, 1113. DOI: 10.3390/genes12081113

Tegtmeier D, Hurka S, Klüber P, Brinkrolf K, Heise P, Vilcinskas A. Cottonseed Press Cake as a Potential Diet for Industrially Farmed Black Soldier Fly Larvae Triggers Adaptations of Their Bacterial and Fungal Gut Microbiota(2021)  Front Microbol. ( Mar 29;12:634503 DOI: 10.3389/fmicb.2021.634503

Tegtmeier D, Hurka S, Mihajlovic S, Bodenschatz M, Schlimbach S, Vilcinskas A. Culture-Independent and Culture-Dependent Characterization of the Black Soldier Fly Gut Microbiome Reveals a Large Proportion of Culturable Bacteria with Potential for Industrial Applications (2021) Microorganisms 20219, 1642. DOI: 10.3390/microorganisms9081642

Tonk M, Růžek D, Vilcinskas A. Compelling Evidence for the Activity of Antiviral Peptides against SARS-CoV-2 (2021) Viruses 2021, 13, 912. DOI: 10.3390/v13050912

Tonk M, Valdés JJ, Cabezas-Cruz A, Vilcinskas A. Potent Activity of Hybrid Arthropod Antimicrobial Peptides Linked by Glycine Spacers (2021) Int. J. Mol. Sci. 2021, 22, 8919. DOI: 10.3390/ijms22168919

Vilcinskas A. Mechanisms of transgenerational immune priming in insects (2021) Developmental & Comparative Immunology, 124, 104205. DOI: 10.1016/j.dci.2021.104205

Voolstra CR, Quigley KM, Davies SW, Everett Parkinson J, Peixoto RS, Aranda M, Baker AC, Barno AR, Barshis DJ, Benzoni F, Bonito V, Bourne DG, Buitrago-López C, Bridge TCL, Xin Chan C, Combosch DJ, Craggs J, Frommlet JC, Herrera S, Quattrini AM, Röthig, T., Reimer, J.D., Rubio-Portillo, E., Suggett, D.J., Villela, H., Ziegler, M., Sweet M. Consensus Guidelines for Advancing Coral Holobiont Genome and Specimen Voucher Deposition (2021)  Frontiers in Marine Science, 8, 701784, DOI: 10.3389/fmars.2021.701784

Wuisan ZG, Kresna IDM, Böhringer N, Lewis K, Schäberle TF. Optimization of heterologous Darobactin A expression and identification of the minimal biosynthetic gene cluster (2021) Metabolic Engineering, 66, 123-136. DOI: 10.1016/j.ymben.2021.04.007

Yang X, Fishlevish E, German M, Gandra P, McEwan R, Billion A, Knorr E, Vilcinskas A, Narva K. Elucidation of microRNA transcriptome in western corn rootworm reveals its dynamic and evolutionary complexity (2021) Genomics, Proteomics & Bioinformatics 16:S1672-0229(21)00014-0. DOI: 10.1016/j.gpb.2019.03.008

Zhuk TS, Skorobohatko OS, Albuquerque W, Zorn H. Scopes and limitations of carbonyl biocatalytic reductions with white-rot fungi (2021) Bioorg Chem, 108, 104651. DOI: 10.1016/j.bioorg.2021.104651

Publikationen 2016-2020

Alle Publikationen der Jahre  2016-2020 finden Sie hier.

Vollständige Publikationslisten aller Standorte können Sie in den jeweiligen Jahresberichten von 2009 bis 2015 einsehen (für 2015 in den Annex Facts).