Our Services

Hands-on research expertise for our clients

For more than 20 years, we have been partnering closely and reliably with organizations across industry and research. We tackle demanding scientific and technical challenges, offering solutions to even the most complex questions. Whether you are a start-up, SME, mid-sized company, or global corporation, we understand your unique needs and deliver tailored, practical solutions.

We look forward to presenting you with a customized proposal and building a successful partnership!

Protein Production

We work with you to plan your recombinant protein production projects and handle the production, purification, and characterization of complex product candidates. With long-standing experience across various microbial production organisms such as bacteria and yeasts, as well as cell-free and plant-based production platforms, we can produce not only simple proteins but also sophisticated, complexly folded proteins in high purity and sufficient quantities.

Our expertise and extensive equipment infrastructure enable us to provide complexly folded (post-translationally modified) proteins, as well as difficult-to-produce or hard-to-purify proteins, from the mid-gram to kilogram scale. Through collaborations with strain developers, we have access to high-performance strains of established production organisms that are already employed in industrial manufacturing facilities. This allows us to provide candidate proteins for toxicity and regulatory studies, for example in the development of new plant protection or plant-strengthening products, as well as food-grade proteins and peptides for the feed or food sector. Furthermore, this enables a rapid transfer of the production process to pilot or industrial scale, facilitating the development of market-ready products.

Our Services

  • Supply of highly pure proteins for feasibility, toxicity, and regulatory studies
  • Production of target proteins from milligram to kilogram scale
  • Early-stage research and comprehensive process development in industry-compatible manufacturing workflows
  • Integration of technological and regulatory considerations for seamless scale-up to industrial production

Your Benefits

  • Access to recombinant proteins for functional testing, feasibility, regulatory, or safety studies
  • Cost-efficient process and purification strategies
  • Early assessment of feasibility and commercial viability for product development
  • Fast-tracked transfer and scale-up to industrial manufacturing

Reference projects for protein production

 

Bacteria used for production of dietary foods

Phenylketonuria (PKU) is a congenital, hereditary disorder of protein metabolism. It inhibits the breakdown of the amino acid phenylalanine, which is associated with significant health consequences for those affected. In the »Phe-Frei« project, we developed a novel phenylalanine-free protein for daily nutrition and the treatment of PKU.

 

Sweet proteins as a new sugar substitute

The aim of the project was to develop novel protein-based sweeteners for beverages, puddings, and yogurt products. Inspired by naturally sweet-tasting proteins, the goal was to identify a protein candidate that is calorie-free and comparable in taste to brown cane sugar, and to develop a biotechnological production process

 

Corona diagnostics from plants

The CDP project demonstrated that the automated transient plant platform at Fraunhofer IME makes it possible to quickly establish a robust process for the production of diagnostic reagents for the detection of coronavirus-specific antibodies. The technology enables the production of reagents sufficient for hundreds of thousands of tests within a few months.