Publications Bioresources

Albuquerque W., Ghezellou P., Li B., Spengler B., Will F., Zorn H., Gand, M. Identification of intact peptides by top-down peptidomics reveals cleavage spots in thermolabile wine proteins (2021) Food Chem, 363, 130437. DOI: 10.1016/j.foodchem.2021.130437

Ali, A., Ellinger, B., Brandt, S.C., Betzel, C., Rühl, M., Wrenger, C., Schlüter, H., Schäfer, W., Brognaro, H., Gand, M. Genome and Secretome Analysis of Staphylotrichum longicolleum DSM105789 Cultured on Agro-Residual and Chitinous Biomass (2021) Microorganisms 2021, 9(8), 1581. DOI: 10.3390/microorganisms9081581

Baudach, A., Vilcinskas A. The European map butterfly Araschnia levana as a model to study the molecular basis and evolutionary ecology of seasonal polyphenism (2021) Insects 12, 325. DOI: 10.3390/insects12040325

Bartling, M., S. Thümecke, A. Vilcinskas, Lee, K.Z. Exposure to low doses of pesticides induces an immune response and the production of nitric oxide in honeybees (2021) Scientific Reports, 11(1), 6819. DOI: 10.1038/s41598-021-86293-0.

Berger, A., Petschenka, G., Degenkolb, T., Geisthardt, M., Vilcinskas, A. Insect Collections as an Untapped Source of Bioactive Compounds—Fireflies (Coleoptera: Lampyridae) and Cardiotonic Steroids as a Proof of Concept (2021) Insects 2021, 12, 689. DOI: 10.3390/insects12080689

Bertrams, W., Lindhauer, N.S., Rieke, M.C., Paas, A., Hoffmann, K., Greene, B., Visekruna, A., Vilcinskas, A., Seidel, K., Schmeck, B. Tribolium castaneum defensin 1 selectively kills Moraxella catarrhalis in an in vitro infection model but does not impair harm commensal bacteria (2021) Virulence 12(1), 1003-101. DOI: 10.1080/21505594.2021.1908741

Bill, M.-K., Brinkmann, S., Oberpaul, M., Patras, M.A., Leis, B., Marner, M., Maitre, M.P., Hammann, P.E., Vilcinskas, A., Schuler, S.M.M. & Schäberle, T.F., Novel Glycerophospholipid, Lipo- and N-acyl Amino Acids from Bacteroidetes: Isolation, Structure Elucidation and Bioactivity (2021) Molecules 2021, 26 (17). DOI: 10.3390/molecules26175195

Birk, F., Brescia, F.F., Fraatz, M.A., Pelzer, R., Zorn, H. Aroma active alkylated pyrazines are produced by Basfia succiniciproducens as by-products of succinic acid production (2021) Flavour and Fragrance Journal, 36 (5), 605-612. DOI: 10.1002/ffj.3674

Böhringer, N., Patras, M.A., Schäberle T.F. Heterologous Expression of Pseudouridimycin and Description of the Corresponding Minimal Biosynthetic Gene Cluster (2021) Molecules 2021, 26 (2). DOI: 10.3390/molecules26020510

Brandt, S.C., Brognaro, H., Ali, A. et al. Insights into the genome and secretome of Fusarium metavorans DSM105788 by cultivation on agro-residual biomass and synthetic nutrient sources (2021) Biotechnol Biofuels 14(74), 22. DOI: 10.1186/s13068-021-01927-9

Brescia F.F., Pitelas W., Yalman S., Popa F., Hausmann H.G., Wende R.C., Fraatz M.A., Zorn H. Formation of diastereomeric dihydromenthofurolactones by Cystostereum murrayi and aroma dilution analysis (ADA) based on dynamic headspace extraction (2021) J Agric Food Chem. DOI: 10.1021/acs.jafc.1c01478

Brinkrolf, K., Shukla, S.P., Griep, S. et al. Genomic analysis of novel Yarrowia-like yeast symbionts associated with the carrion-feeding burying beetle Nicrophorus vespilloides (2021) BMC Genomics 22, 323. DOI: 10.1186/s12864-021-07597-z

Burian, A., Pinn, D., Peralta-Maraver, I., Sweet, M., Mauvisseau, Q., Eyice, O., Bulling, M., Röthig, T., Kratina, P. Predation increases multiple components of microbial diversity in activated sludge communities (2021) The ISME Journal. DOI: 10.1038/s41396-021-01145-z

Carrau, T., B. Lamp, C. Reuscher, A. Vilcinsksas, Lee, K.-Z. Organization of the structural protein region of La Jolla virus Isolated from the invasive pest insect Drosophila suzukii(2021) Viruses 13, 740. DOI: 10.3390/v13050740

Edelmann, D., Leinberger, F.H., Schmid, N.E., Oberpaul, M., Schäberle, T.F., Berghoff, B.A. Elevated Expression of Toxin TisB Protects Persister Cells against Ciprofloxacin but Enhances Susceptibility to Mitomycin C (2021) Microorganisms 2021, 9(5), 943. DOI: 10.3390/microorganisms9050943

Edelmann, D., Oberpaul, M., Schäberle, T.F., Berghoff, B.A. Post-transcriptional deregulation of the tisB/istR-1 toxin–antitoxin system promotes SOS-independent persister formation in Escherichia coli (2021) Environmental microbiology reports, 13(2), 159-168. DOI: 10.1111/1758-2229.12919

Fan, R., Burghardt, J.P., Huang, J.Q., Xiong, T., Czermak, P. Purification of crude fructo-oligosaccharide preparations using probiotic bacteria for the selective fermentation of monosaccharide byproducts (2021) Frontiers in Microbiology, DOI: 10.3389/fmicb.2020.620626

Gegner, J., Vogel, H., Billion, A., Förster, F., Vilcinskas, A. Complete Metamorphosis in Manduca sexta Involves Specific Changes in DNA Methylation Patterns (2021) Front. Ecol. Evol. 9:646281. DOI: 10.3389/fevo.2021.646281

Guzman, J., A. Sombolestani, A. Poehlein, R. Daniel, I Cleenwerck, P. Vandamme &  Vilcinskas, A. Entomobacter blattae gen. nov., sp. nov. – a new member of the Aceto-bacteraceae isolated from the gut of the cockroach Gromphadorhina portentosa (2021) International Journal of Systematic and Evolutionary Microbiology 71(3). DOI: 10.1099/ijsem.0.004666

Hammer A.K., Emrich N.O., Ott J., Birk F., Fraatz M.A., Ley J.P., Geissler T., Bornscheuer U.T., Zorn H. Biotechnological production and sensory evaluation of ω1-unsaturated aldehydes (2021) J Agric Food Chem 69:345–353. DOI: 10.1021/acs.jafc.0c06872

Jiso, A., Demuth, P., Bachowsky, M., Haas, M., Seiwert, N., Heylmann, D., Rasenberger, B., Christmann, M., Dietrich, L., Brunner, T., Riyanti, Schäberle, T.F., Plubrukarn, A., Fahrer, J. Natural Merosesquiterpenes Activate the DNA Damage Response via DNA Strand Break Formation and Trigger Apoptotic Cell Death in p53-Wild-Type and Mutant Colorectal Cancer (2021) Cancers 2021, 13, 3282. DOI: 10.3390/cancers13133282

Kaderka, R., Ferretti, N., Hüsser, M., Lüddecke, T., West, R. Antikuna, a new genus with seven new species from Peru (Araneae: Theraphosidae: Theraphosinae) and the highest altitude record for the family (2021) Journal of natural history 55, 21-22, 1335-140. DOI: 10.1080/00222933.2021.1936680

Karrer, D., Gand, M., Rühl, M. Engineering a lipoxygenase from cyclocybe aegerita towards long chain polyunsaturated fatty acids (2021) AMB Expr, 11(37), 7. (2021). DOI: 10.1186/s13568-021-01195-8

Karrer, D., Gand, M., Rühl, M. Expanding the Biocatalytic Toolbox with a New Type of ene/yne-Reductase from Cyclocybe aegerita (2021) ChemCatChem, 13(9), 2191-2199. DOI: 10.1002/cctc.202002011

Karrer, D., Weigel, V., Hoberg, N. et al. Biotransformation of [U-13C]linoleic acid suggests two independent ketonic- and aldehydic cycles within C8-oxylipin biosynthesis in Cyclocybe aegerita (V. Brig.) Vizzini (2021) Mycol Progress, 20, 929–940. DOI: 10.1007/s11557-021-01719-3

Krahe N.-K., Berger R.G., Witt M., Zorn H., Omarini A.B., Ersoy F. Monokaryotic Pleurotus sapidus strains with intraspecific variability of an alkene cleaving DyP-type peroxidase activity as a result of gene mutation and differential gene expression (2021)  Int J Mol Sci 22:1363; DOI: 10.3390/ijms22031363

Kresna, I.D.M., Linares-Otoya, L., Milzarek, T., Duell, E.R., Mir Mohseni, M., Mettal, U., König, G.M., Gulder, T.A.M., Schäberle, T.F. In vitro characterization of 3-chloro-4-hydroxybenzoic acid building block formation in ambigol biosynthesis (2021) Organic & biomolecular chemistry, 10, 2302-2311. DOI: 10.1039/D0OB02372H

Leannec-Rialland, V., A. Cabezas-Cruz, V. Atanasova, S. Chereau, N. Ponts, M. Tonk, A. Vilcinskas, N. Ferrer, J. Valdés & F. Richard-Forget Tick defensin γ‑core reduces Fusarium graminearum growth and abrogates mycotoxins production with high efficiency (2021) Scientific Reports 11:7962. DOI: 10.1038/s41598-021-86904-w

Lüddecke, T., Herzig, V., von Reumont, B.M., Vilcinskas, A. The biology and evolution of spider venoms (2021) Biol. Rev. DOI: 10.1111/brv.12793

Lüddecke, T., Paas, A., Talmann, L., Kirchhoff, K.N., von Reumont, B.M., Billion, A., Timm, T., Lochnit, G., Vilcinskas, A. A Spider Toxin Exemplifies the Promises and Pitfalls of Cell-Free Protein Production for Venom Biodiscovery (2021) Toxins 2021, 13, 575. DOI: 10.3390/toxins13080575

Lüddecke, T., Vilcinskas, A. Heilen mit Tiergiften: Tödliche Waffen des Tierreichs zur Therapie von Krankheiten nutzbar machen (2021) Chemie in unserer Zeit 55(6), DOI: 10.1002/ciuz.202100005

Maheshwari G., Gessner D.K., Neuhaus K., Most E., Zorn H., Eder K., Ringseis R. Influence of a biotechnologically produced oyster mushroom (Pleurotus sajor-caju) on the gut microbiota and microbial metabolites in obese Zucker rats (2021) J Agric Food Chem 69:1524–1535. DOI: 10.3390/ijms22105241

Maheshwari G., Wen G., Gessner D.K., Ringseis R., Lochnit G., Eder K., Zorn H., Timm T. Tandem mass tag-based proteomics for studying the effects of a biotechnologically produced oyster mushroom against hepatic steatosis in obese Zucker rats (2021) J Proteomics, 242, 104255. DOI: 10.1016/j.jprot.2021.104255

Marschall M.J.M., Ringseis R., Gessner D.K., Grundmann S., Most E., Maheshwari G., Zorn H., Eder K. Effect of ecdysterone on the hepatic transcriptome and lipid metabolism in lean and obese Zucker rats (2021) Int J Mol Sci; 22:5241; DOI: 10.3390/ijms22105241

Mo, T.-X., Huang, X.-S., Zhang, W.-X., Schäberle, T.F., Qin, J.-K., Zhou, D.-X., Qin, X.-Y., Xu, Z.-L., Li, J., Yang, R.-Y. A series of meroterpenoids with rearranged skeletons from an endophytic fungus Penicillium sp. GDGJ-285 (2021) Organic chemistry frontiers, 8 (10), 2232-2241. DOI: 10.1039/D1QO00173F

Oberpaul, M., Brinkmann, S., Marner, M., Mihajlovic, S., Leis, B., Patras, M. A., Hartwig, C., Vilcinskas, A., Hammann, P. E., Schäberle, T. F., Glaeser, J., Spohn, M. Combination of high-throughput microfluidics and FACS technologies to leverage the numbers game in natural product discovery (2021) Microbial Biotechnology 2021. DOI: 10.1111/1751-7915.13872

Orban, A., Weber, A., Herzog, R. et al. Transcriptome of different fruiting stages in the cultivated mushroom Cyclocybe aegerita suggests a complex regulation of fruiting and reveals enzymes putatively involved in fungal oxylipin biosynthesis (2021) BMC Genomics, 22 (324), 23. DOI: 10.1186/s12864-021-07648-5

Rancilhac, L., Irisarri, I., Angelini, C., Arntzen, J.W., Batik, W., Bossuyt, F., Künzel, S., Lüddecke, T., Pasmans, F., Sanchez, E., Weisrock, D., Veith, M., Wielstra, B., Steinhart, S., Hofreiter, M., Vences, M. Phylotranscriptomic evidence for pervasive ancient hybridisation among Old world salamanders (2021) Molecular Phylogenetics and Evolution, 155 (106967), DOI: 10.1016/j.ympev.2020.106967

Röthig, T., Puntin, P., Wong, J.C.Y., Burian, A., McLeod, W., Baker, D.M. Holobiont nitrogen control and its potential for eutrophication resistance in an obligate photosymbiotic jellyfish (2021) Microbiome, 9, 127, DOI: 10.1186/s40168-021-01075-0

Rügen, N., Jenkins, T.P., Wielsch, N., Vogel, H., Hempel, B.-F., Süssmuth, R.D., Ainsworth, S., Cabezas-Cruz, A., Vilcinskas, A., Tonk, M. Hexapod Assassins’ Potion: Venom Composition and Bioactivity from the Eurasian Assassin Bug Rhynocoris iracundus (2021) Biomedicines 2021, 9, 819. DOI: 10.3390/biomedicines9070819

Schmidtberg, H., von Reumont, B., Lemke, S., Vilcinskas, A. & Lüddecke, T. Morphological analysis reveals a compartmentalized duct in the venom apparatus of the wasp spider (Argiope bruennichi) (2021) Toxins, 13, 270. DOI: 10.3390/toxins13040270

Schott, M., Sandmann, M., Cresswell, J., Becher, M., Eichner, G., Brandt, D., Halitschke, D., Krueger, S., Morlock, G., Düring, R.-A.,Vilcinskas A., Meixner, M., Büchler R., & Brandt A. Honeybee colonies compensate for pesticide-induced effects on royal jelly composition and brood survival with increased brood production (2021) Scientific Reports 11(1):62. DOI: 10.1038/s41598-020-79660-w.

Schwabe, M., Griep, S., Schmidtberg, H., Plarre, R., Goesmann, A., Vilcinskas, A., Vogel, H., Brinkrolf, K. Next-Generation Sequencing Analysis of the Tineola bisselliella Larval Gut Transcriptome Reveals Candidate Enzymes for Keratin Digestion (2021) Genes 2021, 12, 1113. DOI: 10.3390/genes12081113

Tegtmeier, D., Hurka, S., Klüber, P., Brinkrolf, K., Heise, P., Vilcinskas, A. Cottonseed press cake as a potential diet for industrially farmed black soldier fly larvae triggers adaptations of their bacterial and fungal gut microbiota (2021) Frontiers in Microbiology 12:634503. DOI: 10.3389/fmicb.2021.634503

Tegtmeier, D., Hurka, S., Mihajlovic, S., Bodenschatz, M., Schlimbach, S., Vilcinskas, A. Culture-Independent and Culture-Dependent Characterization of the Black Soldier Fly Gut Microbiome Reveals a Large Proportion of Culturable Bacteria with Potential for Industrial Applications (2021) Microorganisms 2021, 9, 1642. DOI: 10.3390/microorganisms9081642

Tonk, M., Růžek, D., Vilcinskas, A. Compelling Evidence for the Activity of Antiviral Peptides against SARS-CoV-2 (2021) Viruses 2021, 13, 912. DOI: 10.3390/v13050912

Tonk, M., Valdés, J.J., Cabezas-Cruz, A., Vilcinskas, A. Potent Activity of Hybrid Arthropod Antimicrobial Peptides Linked by Glycine Spacers (2021) Int. J. Mol. Sci. 2021, 22, 8919. DOI: 10.3390/ijms22168919

Vilcinskas, A. Mechanisms of transgenerational immune priming in insects (2021) Developmental & Comparative Immunology, 124, 104205. DOI: 10.1016/j.dci.2021.104205

Voolstra, C.R., Quigley, K.M., Davies, S.W., Everett Parkinson, J.,
Peixoto, R.S., Aranda, M., Baker, A.C., Barno, A.R., Barshis, D.J., Benzoni, F., Bonito, V., Bourne, D.G., Buitrago-López, C., Bridge, T.C.L., Xin Chan, C., Combosch, D.J., Craggs, J., Frommlet, J.C., Herrera, S., Quattrini, A.M.,
Röthig, T., Reimer, J.D., Rubio-Portillo, E., Suggett, D.J., Villela, H., Ziegler, M., Sweet. Cottonseed Press Cake as a Potential Diet for Industrially Farmed Black Soldier Fly Larvae Triggers Adaptations of Their Bacterial and Fungal Gut Microbiota - PubMed (nih.gov)(2021) Frontiers in Marine Science, 8, 701784, DOI: 10.3389/fmars.2021.701784

Wuisan, Z.G., Kresna, I.D.M., Böhringer, N., Lewis, K., Schäberle, T.F. Optimization of heterologous Darobactin A expression and identification of the minimal biosynthetic gene cluster (2021) Metabolic Engineering, 66, 123-136. DOI: 10.1016/j.ymben.2021.04.007

Yang, X., E. Fishlevish, M. German, P. Gandra, R. McEwan, A. Billion, E. Knorr, A. Vilcinskas & K. Narva Elucidation of microRNA transcriptome in western corn rootworm reveals its dynamic and evolutionary complexity (2021) Genomics, Proteomics & Bioinformatics 16:S1672-0229(21)00014-0. DOI: 10.1016/j.gpb.2019.03.008

Zhuk T.S., Skorobohatko O.S., Albuquerque W., Zorn H. Scopes and limitations of carbonyl biocatalytic reductions with white-rot fungi (2021) Bioorg Chem, 108, 104651. DOI: 10.1016/j.bioorg.2021.104651