Albuquerque W, Ghezellou P, Li B, Spengler B, Will F, Zorn H, Gand M. Identification of intact peptides by top-down peptidomics reveals cleavage spots in thermolabile wine proteins (2021) Food Chem, 363, 130437. DOI: 10.1016/j.foodchem.2021.130437
Ali A, Ellinger B, Brandt SC, Betzel C, Rühl M, Wrenger C, Schlüter H, Schäfer W, Brognaro H, Gand M. Genome and Secretome Analysis of Staphylotrichum longicolleum DSM105789 Cultured on Agro-Residual and Chitinous Biomass (2021) Microorganisms 2021, 9(8), 1581. DOI:10.3390/microorganisms9081581
Bartling M, Thümecke S, Vilcinskas A, Lee KZ. Exposure to low doses of pesticides induces an immune response and the production of nitric oxide in honeybees (2021) Scientific Reports, 11(1), 6819. DOI: 10.1038/s41598-021-86293-0.
Baudach A, Vilcinskas A. The European map butterfly Araschnia levana as a model to study the molecular basis and evolutionary ecology of seasonal polyphenism (2021) Insects 12, 325. DOI: 10.3390/insects12040325
Berger A, Petschenka G, Degenkolb T, Geisthardt M, Vilcinskas A. Insect Collections as an Untapped Source of Bioactive Compounds—Fireflies (Coleoptera: Lampyridae) and Cardiotonic Steroids as a Proof of Concept (2021) Insects 2021, 12, 689. DOI: 10.3390/insects12080689
Bertrams W, Lindhauer NS, Rieke MC, Paas A, Hoffmann K, Greene B, Visekruna A, Vilcinskas A, Seidel K, Schmeck B. Tribolium castaneum defensin 1 selectively kills Moraxella catarrhalis in an in vitro infection model but does not impair harm commensal bacteria (2021) Virulence 12(1), 1003-101. DOI: 10.1080/21505594.2021.1908741
Bill M-K, Brinkmann S, Oberpaul M, Patras MA, Leis B, Marner M, Maitre MP, Hammann PE, Vilcinskas A, Schuler SMM, Schäberle TF. Novel Glycerophospholipid, Lipo- and N-acyl Amino Acids from Bacteroidetes: Isolation, Structure Elucidation and Bioactivity (2021) Molecules 2021, 26 (17). DOI: 10.3390/molecules26175195
Birrenbach O, Faust F, Ebrahimi M, Fan R, Czermak P. Recovery and Purification of Protein Aggregates from Cell Lysates using Ceramic Membranes: Fouling Analysis and Modeling of Ultrafiltration, Frontiers in Chemical Engineering (2021) Frontiers in Chemical Engineering section Separation Processes 15, 3, 656345 DOI: 10.3389/fceng.2021.656345
Birk F, Brescia FF, Fraatz MA, Pelzer R, Zorn H. Aroma active alkylated pyrazines are produced by Basfia succiniciproducens as by-products of succinic acid production (2021) Flavour and Fragrance Journal, 36 (5), 605-612. DOI: 0.1002/ffj.3674
Böhringer N, Green R, Liu Y, Mettal U, Marner M, Modaresi SM, Jakob RP, Wuisan ZG, Maier T, Iinishi A, Hiller S, Lewis K, Schäberle TF. Mutasynthetic production and antimicrobial characterisation of Darobactin analogs. (2021) Microbiol Spectr, 2021, 9, Issue 3, e01535-21. DOI: 10.1128/spectrum.01535-21
Böhringer N, Patras MA, Schäberle TF. Heterologous Expression of Pseudouridimycin and Description of the Corresponding Minimal Biosynthetic Gene Cluster (2021) Molecules 2021, 26 (2). DOI: 10.3390/molecules26020510
Brandt SC, Brognaro H, Ali A. et al. Insights into the genome and secretome of Fusarium metavorans DSM105788 by cultivation on agro-residual biomass and synthetic nutrient sources (2021) Biotechnol Biofuels 14(74), 22. DOI: 10.1186/s13068-021-01927-9
Brescia FF, Pitelas W, Yalman S, Popa F, Hausmann HG, Wende RC, Fraatz MA, Zorn H. Formation of diastereomeric dihydromenthofurolactones by Cystostereum murrayi and aroma dilution analysis (ADA) based on dynamic headspace extraction (2021) J Agric Food Chem. DOI: 10.1021/acs.jafc.1c01478
Brinkmann S, Oberpaul M, Glaeser J, Schäberle TF. Two-step generation of monodisperse agarose-solidified double emulsions (w/w/o) excluding an inner oil barrier. (2021) MethodsX, 2021, 8, 101565, DOI: 10.1016/j.mex.2021.101565
Brinkrolf K, Shukla SP, Griep S. et al. Genomic analysis of novel Yarrowia-like yeast symbionts associated with the carrion-feeding burying beetle Nicrophorus vespilloides (2021) BMC Genomics 22, 323. DOI: 10.1186/s12864-021-07597-z
Burian A, Pinn D, Peralta-Maraver I, Sweet M, Mauvisseau Q, Eyice O, Bulling M, Röthig T, Kratina P. Predation increases multiple components of microbial diversity in activated sludge communities (2021) The ISME Journal DOI: 10.1038/s41396-021-01145-z
Carrau T, Lamp B, Reuscher C, Vilcinsksas A, Lee K-Z. Organization of the structural protein region of La Jolla virus Isolated from the invasive pest insect Drosophila suzukii(2021) Viruses 13, 740. DOI: 10.3390/v13050740
Carrau T, Thümecke S, Silva LMR, Perez-Bravo D, Gärtner U, Taubert A, Hermosilla C, Vilcinskas A, Lee KZ. The Cellular Innate Immune Response of the Invasive Pest Insect Drosophila suzukii against Pseudomonas entomophila Involves the Release of Extracellular Traps (2021) Cells 10(12):3320 DOI: 10.3390/cells10123320
Edelmann D, Leinberger FH, Schmid NE, Oberpaul M, Schäberle TF, Berghoff BA. Elevated Expression of Toxin TisB Protects Persister Cells against Ciprofloxacin but Enhances Susceptibility to Mitomycin C (2021) Microorganisms 2021, 9(5), 943. DOI: 10.3390/microorganisms9050943
Edelmann D, Oberpaul M, Schäberle TF, Berghoff BA. Post-transcriptional deregulation of the tisB/istR-1 toxin–antitoxin system promotes SOS-independent persister formation in Escherichia coli (2021) Environmental microbiology reports, 13(2), 159-168. DOI: 10.1111/1758-2229.12919
Fan R, Burghardt JP, Huang JQ, Xiong T, Czermak P. Purification of crude fructo-oligosaccharide preparations using probiotic bacteria for the selective fermentation of monosaccharide byproducts (2021) Frontiers in Microbiology, DOI: 10.3389/fmicb.2020.620626
Fan R, Burghardt JP, Czermak P. Process Design Fundamentals for the Production of Prebiotic Oligosaccharides using Membrane Integrated Reactor Systems (2021) Chemie Ingenieur Technik 93, 1-2, 306-310 DOI: 10.1002/cite.202000127
Fan R, Dresler J, Tissen D, Wen L, Czermak P. In situ purification and enrichment of fructo-oligosaccharides by fermentation with probiotic Bacillus coagulans and selective catalysis using immobilized fructosyltransferase (2021) Bioresource Technology 342, 125969 DOI: 10.1016/j.biortech.2021.125969
Gegner J, Vogel H, Billion A, Förster F, Vilcinskas A. Complete Metamorphosis in Manduca sexta Involves Specific Changes in DNA Methylation Patterns (2021) Front. Ecol. Evol. 9:646281. DOI: 10.3389/fevo.2021.646281
Guzman J, Sombolestani A, Poehlein A, Daniel R, Cleenwerck I, Vandamme P, Vilcinskas A. Entomobacter blattae gen. nov., sp. nov. – a new member of the Aceto-bacteraceae isolated from the gut of the cockroach Gromphadorhina portentosa (2021) International Journal of Systematic and Evolutionary Microbiology 71(3). DOI: 10.1099/ijsem.0.004666
Guzman J, Vilcinskas A. Draft Genome Sequence of Rhodococcus rhodochrous Strain G38GP, Isolated from the Madagascar Hissing Cockroach (2021) Epub Oct 7;10(40):e0077721 DOI: 10.1128/MRA.00777-21
Guzman J, Vilcinskas A. Genome analysis suggests the bacterial family Acetobacteraceae is a source of undiscovered specialized metabolites. (2021) Antonie Van Leeuwenhoek. Epub 2021 Nov 10. PMID: 34761294 DOI: 10.1007/s10482-021-01676-7
Hammer AK, Emrich NO, Ott J, Birk F, Fraatz MA, Ley JP, Geissler T, Bornscheuer UT, Zorn H. Biotechnological production and sensory evaluation of ω1-unsaturated aldehydes (2021) J Agric Food Chem 69:345–353. DOI: 10.1021/acs.jafc.0c06872
Jiso A, Demuth P, Bachowsky M, Haas M, Seiwert N, Heylmann D, Rasenberger B, Christmann M, Dietrich L, Brunner T, Riyanti R, Schäberle TF, Plubrukarn A, Fahrer J. Natural Merosesquiterpenes Activate the DNA Damage Response via DNA Strand Break Formation and Trigger Apoptotic Cell Death in p53-Wild-Type and Mutant Colorectal Cancer (2021) Cancers 2021, 13, 3282. DOI: 10.3390/cancers13133282
Kaderka R, Ferretti N, Hüsser M, Lüddecke T, West R. Antikuna, a new genus with seven new species from Peru (Araneae: Theraphosidae: Theraphosinae) and the highest altitude record for the family (2021) Journal of natural history 55, 21-22, 1335-140. DOI: 10.1080/00222933.2021.1936680
Karrer D, Gand M, Rühl M. Engineering a lipoxygenase from cyclocybe aegerita towards long chain polyunsaturated fatty acids (2021) AMB Expr, 11(37), 7. (2021). DOI: 10.1186/s13568-021-01195-8
Karrer D, Gand M, Rühl, M. Expanding the Biocatalytic Toolbox with a New Type of ene/yne-Reductase from Cyclocybe aegerita (2021) ChemCatChem, 13(9), 2191-2199. DOI: 10.1002/cctc.202002011
Karrer D, Weigel V, Hoberg N. et al. Biotransformation of [U-13C]linoleic acid suggests two independent ketonic- and aldehydic cycles within C8-oxylipin biosynthesis in Cyclocybe aegerita (V. Brig.) Vizzini (2021) Mycol Progress, 20, 929–940. DOI: 10.1007/s11557-021-01719-3
Kirchhoff KN, Billion A, Voolstra CR, Kremb S, Wilke T, Vilcinskas A. Stingray Venom Proteins: Mechanisms of Action Revealed Using a Novel Network Pharmacology Approach. (2021) Mar Drugs 20(1):27 DOI: 10.3390/md20010027
Kleiner Y, Pöverlein C, Klädtke J, Kurz M, König H, Becker J, Mihajlovic S, Zubeil F, Marner M, Vilcinskas A, Schäberle TF, Hammann PE, Schuler SMM, Bauer A. Evaluation of the Floyocidin scaffold as an anti-tuberculosis hit series. (2021) ChemMedChem, DOI: 10.1002/cmdc.202100644
Knorr E, Billion A, Fishilevich E, Tenbusch L, Frey MLF, Rangasamy M, Gandra P, Arora K, Lo W, Geng C, Vilcinskas A, Narva KE. Knockdown of Genes Involved in Transcription and Splicing Reveals Novel RNAi Targets for Pest Control (2021) Front. Agron. 03 September 2021 DOI: 10.3389/fagro.2021.715823
Krahe N-K, Berger RG, Witt M, Zorn H, Omarini AB, Ersoy F. Monokaryotic Pleurotus sapidus strains with intraspecific variability of an alkene cleaving DyP-type peroxidase activity as a result of gene mutation and differential gene expression (2021) Int J Mol Sci 22:1363; DOI: 10.3390/ijms22031363
Kresna IDM, Linares-Otoya L, Milzarek T, Duell ER, Mir Mohseni M, Mettal U, König GM, Gulder TAM, Schäberle TF. In vitro characterization of 3-chloro-4-hydroxybenzoic acid building block formation in ambigol biosynthesis (2021) Organic & biomolecular chemistry, 10, 2302-2311. DOI: 10.1039/D0OB02372H
Kruppa O, Gerlach D, Fan R, Czermak P. Development of a chemically defined medium for Planctopirus limnophila to increase biomass production (2021) Electronic Journal of Biotechnology 54, 86-93 DOI: 10.1016/j.ejbt.2021.09.002
Leannec-Rialland V, Cabezas-Cruz A, Atanasova V, Chereau S, Ponts N, Tonk M, Vilcinskas A, Ferrer N, Valdés J, Richard-Forget F. Tick defensin γ‑core reduces Fusarium graminearum growth and abrogates mycotoxins production with high efficiency (2021) Scientific Reports 11:7962. DOI: 10.1038/s41598-021-86904-w
Lüddecke T, Herzig V, von Reumont BM, Vilcinskas A. The biology and evolution of spider venoms (2021) Biol. Rev. DOI: 10.1111/brv.12793
Lüddecke T, Paas A, Talmann L, Kirchhoff KN, von Reumont BM, Billion A, Timm T, Lochnit G, Vilcinskas A. A Spider Toxin Exemplifies the Promises and Pitfalls of Cell-Free Protein Production for Venom Biodiscovery (2021) Toxins 2021, 13, 575. DOI: 10.3390/toxins13080575
Lüddecke T, Vilcinskas A. Heilen mit Tiergiften: Tödliche Waffen des Tierreichs zur Therapie von Krankheiten nutzbar machen (2021) Chemie in unserer Zeit 55(6), DOI: 10.1002/ciuz.202100005
Maguire N, Ebrahimi M, Fan R, Gießelmann S, Ehlen F, Schütz S, Czermak P. Influence of Ceramic Membrane Surface Characteristics on the Flux Behavior of a Complex Fermentation Broth (2021) Membranes 11, 402 DOI: 10.3390/membranes11060402
Maheshwari G, Gessner DK, Neuhaus K, Most E, Zorn H, Eder K, Ringseis R. Influence of a biotechnologically produced oyster mushroom (Pleurotus sajor-caju) on the gut microbiota and microbial metabolites in obese Zucker rats (2021) Int. J. Mol. Sci. 69:1524–1535. DOI: 10.3390/ijms22105241
Maheshwari G, Wen G, Gessner DK, Ringseis R, Lochnit G, Eder K, Zorn H, Timm T. Tandem mass tag-based proteomics for studying the effects of a biotechnologically produced oyster mushroom against hepatic steatosis in obese Zucker rats (2021) J Proteomics, 242, 104255. DOI: 10.1016/j.jprot.2021.104255
Marschall MJM, Ringseis R, Gessner DK, Grundmann S, Most E, Maheshwari G, Zorn H, Eder K. Effect of ecdysterone on the hepatic transcriptome and lipid metabolism in lean and obese Zucker rats (2021) Int J Mol Sci; 22:5241; DOI: 10.3390/ijms22105241
Mo T-X, Huang X-S, Zhang W-X, Schäberle TF, Qin J-K, Zhou D-X, Qin X-Y, Xu Z-L, Li J, Yang R-Y. A series of meroterpenoids with rearranged skeletons from an endophytic fungus Penicillium sp. GDGJ-285 (2021) Organic chemistry frontiers, 8 (10), 2232-2241. DOI: 10.1039/D1QO00173F
Oberpaul M, Brinkmann S, Marner M, Mihajlovic S, Leis B, Patras MA, Hartwig C, Vilcinskas A, Hammann PE, Schäberle TF, Spohn M, Glaeser J. Combination of high-throughput microfluidics and FACS technologies to leverage the numbers game in natural product discovery (2021) Microbial Biotechnology 2021. DOI: 10.1111/1751-7915.13872
Oestreich A, Suli MI, Gerlach D, Fan R, Czermak P. Media development and process parameter optimization using statistical experimental designs for the production of nonribosomal peptides in Escherichia coli (2021) Electronic Journal of Biotechnology 52, 85-92 DOI: 10.1016/j.ejbt.2021.05.001
Oestreich AM, Reinhardt S, Gerlach D, Fan R, Czermak P. Isolation and purification of a hydrophobic nonribosomal peptide from Escherichia coli fermentation broth (2021) Separations 8, 241 DOI: 10.3390/separations8120241
Orban A, Weber A, Herzog R et al. Transcriptome of different fruiting stages in the cultivated mushroom Cyclocybe aegerita suggests a complex regulation of fruiting and reveals enzymes putatively involved in fungal oxylipin biosynthesis (2021) BMC Genomics, 22 (324), 23. DOI: 10.1186/s12864-021-07648-5
Rancilhac L, Irisarri I, Angelini C, Arntzen JW, Batik W, Bossuyt F, Künzel S, Lüddecke T, Pasmans F, Sanchez E, Weisrock D, Veith M, Wielstra B, Steinhart S, Hofreiter M, Vences M. Phylotranscriptomic evidence for pervasive ancient hybridisation among Old world salamanders (2021) Molecular Phylogenetics and Evolution, 155 (106967), DOI: 10.1016/j.ympev.2020.106967
Röthig T, Puntin P, Wong JCY, Burian A, McLeod W, Baker DM. Holobiont nitrogen control and its potential for eutrophication resistance in an obligate photosymbiotic jellyfish (2021) Microbiome, 9, 127, DOI: 10.1186/s40168-021-01075-0
Rügen N, Jenkins TP, Wielsch N, Vogel H, Hempel B-F, Süssmuth RD, Ainsworth S, Cabezas-Cruz A, Vilcinskas A, Tonk M. Hexapod Assassins’ Potion: Venom Composition and Bioactivity from the Eurasian Assassin Bug Rhynocoris iracundus (2021) Biomedicines 2021, 9, 819. DOI: 10.3390/biomedicines9070819
Schmidtberg H, von Reumont B, Lemke S, Vilcinskas A, Lüddecke T. Morphological analysis reveals a compartmentalized duct in the venom apparatus of the wasp spider (Argiope bruennichi) (2021) Toxins, 13, 270. DOI: 10.3390/toxins13040270
Schott M, Sandmann M, Cresswell J, Becher M, Eichner G, Brandt D, Halitschke D, Krueger S, Morlock G, Düring R-A, Vilcinskas A, Meixner M, Büchler R, Brandt A. Honeybee colonies compensate for pesticide-induced effects on royal jelly composition and brood survival with increased brood production (2021) Scientific Reports 11(1):62. DOI: 10.1038/s41598-020-79660-w.
Schwabe M, Griep S, Schmidtberg H, Plarre R, Goesmann A, Vilcinskas A, Vogel, H., Brinkrolf, K. Next-Generation Sequencing Analysis of the Tineola bisselliella Larval Gut Transcriptome Reveals Candidate Enzymes for Keratin Digestion (2021) Genes 2021, 12, 1113. DOI: 10.3390/genes12081113
Tegtmeier D, Hurka S, Klüber P, Brinkrolf K, Heise P, Vilcinskas A. Cottonseed press cake as a potential diet for industrially farmed black soldier fly larvae triggers adaptations of their bacterial and fungal gut microbiota (2021) Frontiers in Microbiology 12:634503. DOI: 10.3389/fmicb.2021.634503
Tegtmeier D, Hurka S, Mihajlovic S, Bodenschatz M, Schlimbach S, Vilcinskas A. Culture-Independent and Culture-Dependent Characterization of the Black Soldier Fly Gut Microbiome Reveals a Large Proportion of Culturable Bacteria with Potential for Industrial Applications (2021) Microorganisms 2021, 9, 1642. DOI: 10.3390/microorganisms9081642
Tegtmeier D, Hurka S, Klüber P, Brinkrolf K, Heise P, Vilcinskas A. Cottonseed Press Cake as a Potential Diet for Industrially Farmed Black Soldier Fly Larvae Triggers Adaptations of Their Bacterial and Fungal Gut Microbiota(2021) Front Microbol. (nih.gov) Mar 29;12:634503 DOI: 10.3389/fmicb.2021.634503
Tonk M, Růžek D, Vilcinskas A. Compelling Evidence for the Activity of Antiviral Peptides against SARS-CoV-2 (2021) Viruses 2021, 13, 912. DOI: 10.3390/v13050912
Tonk M, Valdés JJ, Cabezas-Cruz A, Vilcinskas A. Potent Activity of Hybrid Arthropod Antimicrobial Peptides Linked by Glycine Spacers (2021) Int. J. Mol. Sci. 2021, 22, 8919. DOI: 10.3390/ijms22168919
Vilcinskas A. Mechanisms of transgenerational immune priming in insects (2021) Developmental & Comparative Immunology, 124, 104205. DOI: 10.1016/j.dci.2021.104205
Voolstra CR, Quigley KM, Davies SW, Everett Parkinson J, Peixoto RS, Aranda M, Baker AC, Barno AR, Barshis DJ, Benzoni F, Bonito V, Bourne DG, Buitrago-López C, Bridge TCL, Xin Chan C, Combosch DJ, Craggs J, Frommlet JC, Herrera S, Quattrini AM, Röthig, T., Reimer, J.D., Rubio-Portillo, E., Suggett, D.J., Villela, H., Ziegler, M., Sweet M. Consensus Guidelines for Advancing Coral Holobiont Genome and Specimen Voucher Deposition (2021) Frontiers in Marine Science, 8, 701784, DOI: 10.3389/fmars.2021.701784
Wuisan ZG, Kresna IDM, Böhringer N, Lewis K, Schäberle TF. Optimization of heterologous Darobactin A expression and identification of the minimal biosynthetic gene cluster (2021) Metabolic Engineering, 66, 123-136. DOI: 10.1016/j.ymben.2021.04.007
Yang X, Fishlevish E, German M, Gandra P, McEwan R, Billion A, Knorr E, Vilcinskas A, Narva K. Elucidation of microRNA transcriptome in western corn rootworm reveals its dynamic and evolutionary complexity (2021) Genomics, Proteomics & Bioinformatics 16:S1672-0229(21)00014-0. DOI: 10.1016/j.gpb.2019.03.008
Zhuk TS, Skorobohatko OS, Albuquerque W, Zorn H. Scopes and limitations of carbonyl biocatalytic reductions with white-rot fungi (2021) Bioorg Chem, 108, 104651. DOI: 10.1016/j.bioorg.2021.104651