| year |
Titel / Autor |
Medium |
| 2024 |
Draft genome sequences of 21 Pedobacter strains isolated from amphibian specimens. Zumkeller CM, Bletz MC, Rakotoarison A, Sabino-Pinto J, Reiter S, Spohn M, Schwengers O, Goesmann A, Vences M, Mihajlovic S, Schäberle TF. |
Microbiol Resour Announc; 13(4):e0118523. DOI: 10.1128/mra.01185-23. |
| 2024 |
Draft genome sequence of Galbibacter sp. PAP.153, isolated from a marine sponge in Papua, Indonesia. Riyanti, Zumkeller CM, Spohn M, Mihajlovic S, Schwengers O, Goesmann A, Riviani R, Meinita MDN, Hastuti DWB, Prihatiningsih I, Dewi R, Schäberle TF. |
Microbiol Resour Announc; 13(6):e0129723. DOI: 10.1128/mra.01297-23. |
| 2024 |
5'-Methoxyarmillane, a Bioactive Sesquiterpenoid Aryl Ester from the Fungus Armillaria ostoyae. Orban A, Eichberg J, Marner M, Breuer S, Patras M, Mettal U, Schäberle T, Rühl M. |
Chembiochem:e202400168. DOI: 10.1002/cbic.202400168. |
| 2024 |
Design, synthesis and antimycobacterial activity of imidazo1,5-aquinolines and their zinc-complexes. Marner M, Kulhanek N, Eichberg J, Hardes K, Molin MD, Rybniker J, Kirchner M, Schäberle TF, Göttlich R. |
RSC Med Chem; 15(5):1746–50. DOI: 10.1039/d4md00086b. |
| 2024 |
Determining the pharmacological potential and biological role of linear pseudoscorpion toxins via functional profiling. Erkoc P, Schiffmann S, Ulshöfer T, Henke M, Marner M, Krämer J, Predel R, Schäberle TF, Hurka S, Dersch L, Vilcinskas A, Fürst R, Lüddecke T. |
iScience; 27(7):110209. DOI: 10.1016/j.isci.2024.110209cell.com. |
| 2024 |
Physiochemical interaction between osmotic stress and a bacterial exometabolite promotes plant disease.
Getzke F, Wang L, Chesneau G, Böhringer N, Mesny F, Denissen N, Wesseler H, Adisa PT, Marner M, Schulze-Lefert P, Schäberle TF, Hacquard S. |
Nat Commun; 15(1):4438. DOI: 10.1038/s41467-024-48517-5nature.com. |
| 2024 |
Nanoliter-scale selection of optimized bioengineered peptide antibiotics that rescue mice with bacterial lung infection. Böhringer N, Wuisan ZG, Marner M, Kresna IDM, Mettal U, Schmitt S, Reiter S, Liu Y, Brinkrolf K, Rupp O, Schwengers O, Findeisen J, Herold S, Matt U, Schäberle TF. |
bioRxiv 2024.05.30.596553. DOI: 10.1101/2024.05.30.596569biorxiv.org. |
| 2024 |
Sponge-Based Ecofriendly Antifouling: Field Study on Nets, Molecular Docking with Agelasine Alkaloids Balansa W, Riyanti, Manurung UN, Tomasoa AM, Hanif N, Rieuwpassa FJ, Schäberle TF. |
Tropical Journal of Natural Product Research (TJNPR); 8(1).
DOI: 10.26538/tjnpr/v8i1.29. |
| 2023 |
Is a Modified Actin the Key to Toxin Resistance in the Nudibranch Chromodoris? A Biochemical and Molecular Approach. Hertzer C, Undap N, Papu A, Bhandari D, Aatz S, Kehraus S, Kaligis F, Bara R, Schäberle T, Wägele H, König G. |
Diversity; 15(2):304. DOI: 10.3390/d15020304mdpi.com. |
| 2023 |
Cofunctioning of bacterial exometabolites drives root microbiota establishment. Getzke F, Hassani MA, Crüsemann M, Malisic M, Zhang P, Ishigaki Y, Böhringer N, Jiménez Fernández A, Wang L, Ordon J, Ma K-W, Thiergart T, Harbort CJ, Wesseler H, Miyauchi S, Garrido-Oter R, Shirasu K, Schäberle TF, Hacquard S, Schulze-Lefert P.
|
Proc Natl Acad Sci U S A; 120(15):e2221508120. DOI: 10.1073/pnas.2221508120pnas.org. |
| 2023 |
Darobactin B Stabilises a Lateral-Closed Conformation of the BAM Complex in E. coli Cells. Haysom SF, Machin J, Whitehouse JM, Horne JE, Fenn K, Ma Y, El Mkami H, Böhringer N, Schäberle TF, Ranson NA, Radford SE, Pliotas C. |
Angew Chem Int Ed Engl; 62(34):e202218783. DOI: 10.1002/anie.202218783. |
| 2023 |
Extracts of Talaromyces purpureogenus Strains from Apis mellifera Bee Bread Inhibit the Growth of Paenibacillus spp. Vocadlova K, Lüddecke T, Patras MA, Marner M, Hartwig C, Benes K, Matha V, Mraz P, Schäberle TF, Vilcinskas A. |
Microorganisms; 11(8). DOI: 10.3390/microorganisms11082067. |
| 2023 |
Full Profiling of GE81112A, an Underexplored Tetrapeptide Antibiotic with Activity against Gram-Negative Pathogens Schuler SMM, Jürjens G, Marker A, Hemmann U, Rey A, Yvon S, Lagrevol M, Hamiti M, Nguyen F, Hirsch R, Pöverlein C, Vilcinskas A, Hammann P, Wilson DN, Mourez M, Coyne S, Bauer A. |
Microbiol Spectr. DOI: 10.1128/spectrum.02247-22. |
| 2023 |
Antimicrobial Activity of Ceftazidime-Avibactam, Ceftolozane-Tazobactam, Cefiderocol, and Novel Darobactin Analogs against Multidrug-Resistant Pseudomonas aeruginosa Isolates from Pediatric and Adolescent Cystic Fibrosis Patients Marner M, Kolberg L, Horst L, Böhringer N, Hübner J, Kresna DM, Liu Y, Mettal U, Wang L, Meyer-Bühn M, Mihajlovic S, Kappler M, Schäberle TF, von Both U. |
Microbiol Spectr. DOI: 10.1128/spectrum.04437-22. |
| 2023 |
Draft Genome Sequences of Algoriphagus sp. Strain PAP.12 and Roseivirga sp. Strain PAP.19, Isolated from Marine Samples from Papua, Indonesia Riyanti, Zumkeller CM, Spohn M, Mihajlovic S, Schwengers O, Goesmann A, Choironi NA, Schäberle TF, Harwoko H |
Microbiology Resource Announcements DOI: 10.1128/mra.01264-22 |
| 2023 |
Draft Genome Sequence of Sinomicrobium sp. Strain PAP.21, Isolated from a Coast Sample of Papua, Indonesia Riyanti, Zumkeller CM, Spohn M, Mihajlovic S, Schwengers O, Goesmann A, Riviani R, Meinita MDN, Schäberle TF, Harwoko H |
Microbiology Resource Announcements. DOI: 10.1128/mra.01268-22. |
| 2023 |
Metabolic engineering of the shikimate pathway in Amycolatopsis strains for optimized glycopeptide antibiotic production Goldfinger V, Spohn M, Rodler JP, Sigle M, Kulik A, Cryle MJ, Rapp J, Link H, Wohlleben W, Stegmann E. |
Metabolic Engineering. DOI: 10.1016/j.ymben.2023.05.005. |
| 2023 |
Total Synthesis of Floyocidin B: 4,5-Regioselective Functionalization of 2-Chloropyridines Kleiner Y, Bauer A, Hammann P, Schuler SMM, Pöverlein C. |
Chemistry 5(1), 168-178. DOI: 10.3390/chemistry5010014. |
| 2023 |
Production of Antimicrobial Compounds by Homologous and Heterologous Expression. Kresna IDM, Wuisan ZG, Schäberle TF. |
Methods Mol Biol. DOI: 10.1007/978-1-0716-2855-3_4. |
| 2022 |
Bioactive Natural Products from Bacteroidetes Brinkmann S, Spohn MS, Schäberle TF.
|
Nat. Prod. Rep. 39, 1045-1065.
DOI: 10.1039/d1np00072a. |
2022
|
Discovery of Marine Natural Products as Promising Antibiotics against Pseudomonas aeruginosa Li H, Maimaitiming M, Zhou Y, Li H, Wang P, Liu Y, Schäberle TF, Liu Z, Wang C-Y. |
Mar Drugs 4;20(3):192. DOI: 10.3390/md20030192. |
| 2022 |
Genomic and Chemical Decryption of the Bacteroidetes Phylum for Its Potential to Biosynthesize Natural Products Brinkmann S, Kurz M, Patras MA, Hartwig C, Marner M, Leis B, Billion A, Kleiner Y, Bauer A, Toti L, Pöverlein C, Hammann PE, Vilcinskas A, Glaeser J, Spohn MS, Schäberle TF. |
Antimicrobial Chemotherapy 10 (3). DOI: 10.1128/spectrum.02479-21. |
| 2022 |
Genome Mining-Guided Discovery and Characterization of the PKS-NRPS-Hybrid Polyoxyperuin produced by a Marine-Derived Streptomycete Kresna ID, Wuisan ZG, Pohl JM, Mettal U, Linares-Otoya V, Gand M, Marner M, Linares-Otoya L, Böhringer N, Vilcinskas A, Schäberle TF. |
J Nat Prod, 85, 4, 888–898. DOI: 10.1021/acs.jnatprod.1c01018.
|
| 2022 |
Identification, Characterization, and Synthesis of Natural Parasitic Cysteine Protease Inhibitors: Pentacitidins Are More Potent Falcitidin Analogues Brinkmann S, Semmler S, Kersten C, Patras MA, Kurz M, Fuchs N, Hammerschmidt SJ, Legac J, Hammann PE, Vilcinskas A, Rosenthal PJ, Schirmeister T, Bauer A, Schäberle TF. |
ACS Chem Biol, 18;17(3):576-589. DOI: 10.1021/acschembio.1c00861. |
| 2022 |
Trichoderma-Derived Pentapeptides from the Infected Nest Mycobiome of the Subterranean Termite Coptotermes testaceus Oberpaul M, Spohn M, Brinkmann S, Mihajlovic S, Marner M, Patras MA, Toti L, Kurz M, Hammann PE, Vilcinskas A, Glaeser J, Schäberle TF. |
Chembiochem, 23 (10), e202100698. DOI: 10.1002/cbic.202100698. |
| 2021 |
Novel Glycerophospholipid, Lipo- and N-acyl Amino Acids from Bacteroidetes: Isolation, Structure Elucidation and Bioactivity. Bill M-K, Brinkmann S, Oberpaul M, Patras MA, Leis B, Marner M, Maitre MP, Hammann PE, Vilcinskas A, Schuler SMM, Schäberle TF. |
Molecules 26 (17). DOI: 10.3390/molecules26175195. |
| 2021 |
Mutasynthetic production and antimicrobial characterisation of Darobactin analogs. Böhringer N, Green R, Liu Y, Mettal U, Marner M, Modaresi SM, Jakob RP, Wuisan ZG, Maier T, Iinishi A, Hiller S, Lewis K, Schäberle TF. |
Microbiol Spectr 9, Issue 3, e01535-21. DOI: 10.1128/spectrum.01535-21. |
| 2021 |
Heterologous Expression of Pseudouridimycin and Description of the Corresponding Minimal Biosynthetic Gene Cluster. Böhringer N, Patras MA, Schäberle TF. |
Molecules 26 (2). DOI: 10.3390/molecules26020510. |
| 2021 |
Two-step generation of monodisperse agarose-solidified double emulsions (w/w/o) excluding an inner oil barrier. Brinkmann S, Oberpaul M, Glaeser J, Schäberle TF. |
MethodsX 8, 101565. DOI: 10.1016/j.mex.2021.101565. |
| 2021 |
Elevated Expression of Toxin TisB Protects Persister Cells against Ciprofloxacin but Enhances Susceptibility to Mitomycin C Edelmann D, Leinberger FH, Schmid NE, Oberpaul M, Schäberle TF, Berghoff BA. |
Microorganisms 9(5), 943. DOI: 10.3390/microorganisms9050943. |
| 2021 |
Post-transcriptional deregulation of the tisB/istR-1 toxin–antitoxin system promotes SOS-independent persister formation in Escherichia coli
Edelmann D, Oberpaul M, Schäberle TF, Berghoff BA. |
Environmental microbiology reports 13(2), 159-168. DOI: 10.1111/1758-2229.12919. |
| 2021 |
Natural Merosesquiterpenes Activate the DNA Damage Response via DNA Strand Break Formation and Trigger Apoptotic Cell Death in p53-Wild-Type and Mutant Colorectal Cancer Jiso A, Demuth P, Bachowsky M, Haas M, Seiwert N, Heylmann D, Rasenberger B, Christmann M, Dietrich L, Brunner T, Riyanti R, Schäberle TF, Plubrukarn A, Fahrer J. |
Cancers 13, 3282. DOI: 10.3390/cancers13133282. |
| 2021 |
Evaluation of the Floyocidin scaffold as an anti-tuberculosis hit series. Kleiner Y, Pöverlein C, Klädtke J, Kurz M, König H, Becker J, Mihajlovic S, Zubeil F, Marner M, Vilcinskas A, Schäberle TF, Hammann PE, Schuler SMM, Bauer A. |
ChemMedChem. DOI: 10.1002/cmdc.202100644. |
| 2021 |
In vitro characterization of 3-chloro-4-hydroxybenzoic acid building block formation in ambigol biosynthesis Kresna IDM, Linares-Otoya L, Milzarek T, Duell ER, Mir Mohseni M, Mettal U, König GM, Gulder TAM, Schäberle TF. |
Organic & biomolecular chemistry 10, 2302-2311. DOI: 10.1039/D0OB02372H. |
| 2021 |
A series of meroterpenoids with rearranged skeletons from an endophytic fungus Penicillium sp. GDGJ-285
Mo T-X, Huang X-S, Zhang W-X, Schäberle TF, Qin J-K, Zhou D-X, Qin X-Y, Xu Z-L, Li J, Yang R-Y. |
Organic chemistry frontiers 8 (10), 2232-2241. DOI: 10.1039/D1QO00173F. |
| 2021 |
Combination of high-throughput microfluidics and FACS technologies to leverage the numbers game in natural product discovery. Oberpaul M, Brinkmann S, Marner M, Mihajlovic S, Leis B, Patras MA, Hartwig C, Vilcinskas A, Hammann PE, Schäberle TF, Glaeser J, Spohn M. |
Microbial Biotechnology 2021 Jun 24. DOI: 10.1111/1751-7915.13872. |
| 2021 |
Optimization of heterologous Darobactin A expression and identification of the minimal biosynthetic gene cluster Wuisan ZG, Kresna IDM, Böhringer N, Lewis K, Schäberle TF. |
Metabolic Engineering 66, 123-136. DOI: 10.1016/j.ymben.2021.04.007. |
| 2020 |
The Gram-Positive Bacterium Leuconostoc pseudomesenteroides Shows Insecticidal Activity against Drosophilid and Aphid Pests. Hiebert N, Kessel T, Skaljac M, Spohn M, Vilcinskas A, Lee KZ. |
Insects 11 (8). DOI: 10.3390/insects11080471. |
| 2020 |
Molecular Networking-Guided Discovery and Characterization of Stechlisins, a Group of Cyclic Lipopeptides from a Pseudomonas sp. Marner M, Patras MA, Kurz M, Zubeil F, Förster F, Schuler S, Bauer A, Hammann P, Vilcinskas A, Schäberle TF, Glaeser J. |
Journal of Natural Products 83 (9), 2607-2617. DOI: 10.1021/acs.jnatprod.0c00263. |
| 2020 |
High-Throughput cultivation for the selective isolation of Acidobacteria from termite nests. Oberpaul M, Zumkeller CM, Culver T, Spohn M, Mihajlovic S, Leis B, Glaeser SP, Plarre R, McMahon DP, Hammann P, Schäberle TF, Glaeser J, Vilcinskas A. |
Frontiers in Microbiology 11(597628). DOI: 10.3389/fmicb.2020.597628. |
| 2020 |
Sustainable Low-Volume Analysis of Environmental Samples by Semi-Automated Prioritization of Extracts for Natural Product Research (SeaPEPR). Riyanti R, Marner M, Hartwig C, Patras MA, Wodi SIM, Rieuwpassa FJ, Ijong FG, Balansa W, Schäberle TF. |
Marine Drugs 18 (12). DOI: 10.3390/md18120649. |
| 2019 |
A new antibiotic selectively kills Gram-negative pathogens. Imai Y, Meyer KJ, Iinishi A, Favre-Godal Q, Green R, Manuse S, Caboni M, Mori M, Niles S, Ghiglieri M, Honrao C, Ma X, Guo JJ, Makriyannis A, Linares-Otoya L, Böhringer N, Wuisan ZG, Kaur H, Wu R, Mateus A, Typas A, Savitski MM, Espinoza JL, O’Rourke A, Nelson KE, Hiller S, Noinaj N, Schäberle TF, D’Onofrio A, Lewis K. |
Nature 576 (7787), 459-464. DOI: 10.1038/s41586-019-1791-1. |
| 2019 |
Transmission of a Protease-Secreting Bacterial Symbiont Among Pea Aphids via Host Plants. Skaljac M, Vogel H, Wielsch N, Mihajlovic S, Vilcinskas A. |
Frontiers in physiology 2019, 10, 438. DOI: 10.3389/fphys.2019.00438. |
| 2018 |
Profiling antimicrobial peptides from the medical maggot Lucilia sericata as potential antibiotics for MDR Gram-negative bacteria. Hirsch R, Wiesner J, Marker A, Pfeifer Y, Bauer A, Hammann PE, Vilcinskas A. |
Journal of Antimicrobial Chemotherapy 74 (1), 96-107. DOI: 10.1093/jac/dky386. |
| 2017 |
Svetamycins A–G, Unusual Piperazic Acid-Containing Peptides from Streptomyces sp. Dardić D, Lauro G, Bifulco G, Laboudie P, Sakhaii P, Bauer A, Vilcinskas A, Hammann PE, Plaza A. |
The Journal of Organic Chemistry 82 (12), 6032-6043. DOI: 10.1021/acs.joc.7b00228. |
| 2014 |
Fraunhofer to mine Sanofi microbial collection. Fox, JL. |
Nat Biotechnol 32, 305. DOI: 10.1038/nbt0414-305a. |
Fraunhofer Institute for Molecular Biology and Applied Ecology IME
