Strain Collection

The Fraunhofer Strain Collection – your source for microbial innovation potential!

© Fraunhofer IME | Desirée Schulz
Prof. Dr. Till Schäberle Head of the Natural Products Research Department with samples from the Fraunhofer Strain Collection.
© Rolf K. Wegst
Agar plates from the Fraunhofer Strain Collection.
© Rolf K. Wegst
Dr. Sanja Mihajlovic leader of the Strain collection collects frozen samples.

In 2020, Fraunhofer IME received one of the world's largest microbial strain collections with over 110,000 strains from Sanofi

Our well-curated collection, which consists of 79% bacteria and 21% fungi, includes several functional sub-collections, such as the soil collection, which we use for the search for e.g., new active pharmaceutical ingredients. The food collection, which includes strains listed in the QPS (Qualified Presumption of Safety) list and edible fungi (basidiomycetes). A strain collection for biocontrol and plant growth promotion, which includes beneficial strains such as entomopathogenic fungi and Pseudomonas spp. The Marine Collection, which includes microbes isolated from marine algae, invertebrates, coral reefs and marine sediments. We also have an Arthropod Collection, which focuses on gut-related microorganisms. In addition, we hold little-studied bacteria and provide access to rare phylogenetic branches, including Acidobacteria.

With access to well-characterised strains and their functionalities, we have been enabling our customers to develop innovative and sustainable biotechnological solutions with wide-ranging applications such as pharmaceutical, veterinary, agricultural and food. Our collection is the result of over 70 years of dedicated industrial endeavour in the isolation, cultivation and extraction of microbial compounds.

All strains comply with access and benefit-sharing (ABS) regulations in accordance with the Nagoya Protocol.

Our custom in-house strain management system links each processed strain to its biochemical, genetic, analytical, and ABS data. This ensures that we can identify and retrieve compounds with specific properties while maintaining the integrity of our customers' data. 

 

Isolation methods:

  • classical isolation
  • microtiter process
  •  microfluidics

 

Technical details:

  • microorganisms are stored in multiple copies (appx. 650,000 vials)
  • appx. 20,000 microorganisms are freeze-dried and refrigerated 
  • appx. 100,000 microorganisms are cryopreserved (-80 °C, -140 °C)

Functional sub-collections

Our collection contains a diverse selection of microorganisms, including bacteria (79%) and fungi (21%), as well as microbial natural product extracts and purified compounds. It is divided into several functional sub-collections:

Bacteria Collection

 
  • We discover bacteria and provide access to rare phylogenetic branches, including Acidobacteria.

Food Collection

 

  • Our food collection includes strains listed in the QPS (Qualified Presumption of Safety) list, as well as edible fungi (basidiomycetes).

Soil Collection

 
  • We use our soil collection to search for new pharmaceutical and veterinary agents.

Biological control and promotion of plant growth

  • Our collection for biocontrol and plant growth promotion includes useful strains such as entomopathogenic fungi and Pseudomonas spp.

Marine Collection

 
  • Our Marine Collection includes microbes isolated from seaweed, invertebrates, coral reefs and marine sediments.

Arthropod Collection

 
  • We use our soil collection to search for new pharmaceutical and veterinary agents.

 

The Fraunhofer Strain collection

Hessischer Rundfunk

Our Projects

 

Sustainable animal health solutions

 

»Terpenoids from fungi«

Discovery of new terpenoids, evaluation of potential areas of application and production of compounds and samples for industrial use.

 

»Recovering beta-lactam antibiotic activity against multi-drug resistant Gram-negative bacteria«

 

»ProBioControl«

Profiling of natural product-producing microorganisms for the isolation of new antifungal natural products and their potential application as biocontrol agents  

How you work with us

If you are interested in collaborating or conducting research and development, please contact us!

Dr. Sanja Mihajlovic

Curator of the »Strain Collection«

Fraunhofer Institute for Molecular Biology and Applied Ecology IME
Ohlebergsweg 12
35392 Giessen, Germany

Phone +4964197219266

 

Natural Products