Bioinformatics

1. Data Acquisition & Integration

• Multi-omics (genomics, transcriptomics, proteomics, metabolomics)
• Environmental and phenotypic data
• Public databases and client data

2. Quality Control & Standardization

• Automated data cleaning
• Harmonization of formats
• Reproducible workflows

3. AI-Driven Analysis

• Machine learning and statistical modelling
• Biomarker discovery
• Predictive analytics
• Network and pathway analysis

4. Interpretation & Reporting

• Clear visualizations
• Biological interpretation
• Decision-ready reports

Let’s turn your data into solutions.

• Have a dataset but don’t know where to start?
• Planning an omics experiment?
• Need AI-driven insights for a project?

Contact us for a free initial consultation.

Känel A, Roelfs KU, Wissing M, Lenzen B, Klein M, Twyman RM, Noll GA, Prüfer D

Vernalization reveals distinct roles of FLOWERING LOCUS T homologs in floral transition of perennial Taraxacum koksaghyz.

(2026) Plant Science 112743. https://doi.org/10.1016/j.plantsci.2025.112743

Essfeld, F., Ayobahan, S.U., Strompen, J., Alvincz, J., Schmidt-Posthaus, H., Woelz, J., Mueller, T., Ringbeck, B., Teigeler, M., Eilebrecht, E., Eilebrecht, S.

Transcriptomic Point of Departure (tPOD) of androstenedione in zebrafish embryos as a potential surrogate for chronic endpoints.

(2024) Science of the Total Environment. doi.org/10.1016/j.scitotenv.2024.176026

Mäckelmann S., Känel A., Kösters L.M., Lyko P., Prüfer D., Noll G.A., Wicke S.

Gene complementation analysis indicates that parasitic dodder plants do not depend on the host FT protein for flowering.

(2024) Plant Communications. https://doi.org/10.1016/j.xplc.2024.100826

Roelfs KU., Känel A., Twyman R.M., Prüfer D., Schulze Gronover C.

Epigenetic variation in early and late flowering plants of the rubber-producing Russian dandelion Taraxacum koksaghyz provides insights into the regulation of flowering time.

(2024) Scientific Reports 14, 4283. https://doi.org/10.1038/s41598-024-54862-8

Riekötter, J, Oklestkova, J, Muth, J, Twyman, RM, Epping, J.

Transcriptomic analysis of Chinese yam (Dioscorea polystachya Turcz.) variants indicates brassinosteroid involvement in tuber development.

(2023) Frontiers Nutrition. https://doi.org/10.3389/fnut.2023.1112793

Solís, J. L., Muth, J., Canales, J., Lizana, C., Pruefer, D., Riegel, R., & Behn, A.

Allelic diversity of three anthocyanin synthesis genes in accessions of native Solanum tuberosum L. ssp. tuberosum at the Potato Genebank of the Universidad Austral de Chile.

(2022) Genetic resources and crop evolution, 69(1), 297-314. https://doi.org/10.1007/s10722-021-01230-4

Benninghaus, V.A., Van Deenen, N., Müller, B., Roelfs, K.-U., Lassowskat, I., Finkemeier, I., Prüfer, D., Gronover, C.S.

Comparative proteome and metabolome analyses of latex-exuding and non-exuding Taraxacum koksaghyz roots provide insights into laticifer biology.

(2020) Journal of Experimental Botany, 71 (4), 1278-1293. https://doi.org/10.1093/jxb/erz512

Lüddecke, T., Hurka, S., Dresler, J., Lübcke, T., von Wirth, V., Lochnit, G., Timm, T., Herzig, V., Vilcinskas, A.

Comparative venomics suggests an evolutionary adaption of spider venom from predation to defense.

(2025) Commun Biol 8, 1496. https://doi.org/10.1038/s42003-025-09015-6

Avella, I., Schulte, L., Damm, M., Uhrig, L., Cabrera-Orefice, A., et al. 

Venomics of the Arabian saw-scaled viper (Echis coloratus) through transcriptome-guided proteomics and in vitro functional profiling.

(2025) PLOS Neglected Tropical Diseases 19(8): e0013439. https://doi.org/10.1371/journal.pntd.0013439

Klüber, P., Gurusinga, F. F., Hurka, S., Vilcinskas, A., Tegtmeier D.

Turning trash into treasure: Hermetia illucens microbiome and biodegradation of industrial side streams. 

(2024) Appl Environ Microbiol 90:e00991-24. https://doi.org/10.1128/aem.00991-24

Brinkmann S, Kurz M, Patras MA, Hartwig C, Marner M, Leis B, Billion A, Kleiner Y, Bauer A, Toti L, Pöverlein C, Hammann PE, Vilcinskas A,Glaeser J,Spohn M, Schäberle TF.

Genomic and Chemical Decryption of the Bacteroidetes Phylum for Its Potential to Biosynthesize Natural Products. 

(2022) Microbiol Spectr 10:e02479-21. https://doi.org/10.1128/spectrum.02479-21

Hurka, S., Brinkrolf, K., Özbek, R., Förster, F., Billion, A., Heep, J., Timm, T., Lochnit, G., Vilcinskas, A., & Lüddecke, T.

Venomics of the Central European Myrmicine Ants Myrmica rubra and Myrmica ruginodis.

(2022) Toxins, 14(5), 358. https://doi.org/10.3390/toxins14050358

Kirchhoff, K. N., Billion, A., Voolstra, C. R., Kremb, S., Wilke, T., & Vilcinskas, A.

Stingray Venom Proteins: Mechanisms of Action Revealed Using a Novel Network Pharmacology Approach. 

(2022) Marine Drugs, 20(1), 27. https://doi.org/10.3390/md20010027

Yang, X., Fishilevich, E., German, M. A., Gandra, P., McEwan, R. E., Billion, A., Knorr, E., Vilcinskas, A., Narva, K. E.

Elucidation of the MicroRNA Transcriptome in Western Corn Rootworm Reveals Its Dynamic and Evolutionary Complexity.

(2021) Genomics, Proteomics & Bioinformatics, 19( 5), 800-814. https://doi.org/10.1016/j.gpb.2019.03.008.

Gegner, J., Vogel, H., Billion, A., Förster, F.  &Vilcinskas, A.

Complete Metamorphosis in Manduca sexta Involves Specific Changes in DNA Methylation Patterns.

(2021) Front. Ecol. Evol. doi: 10.3389/fevo.2021.646281