Analytics

Insights into your samples

Join us on a deep dive into the world of your samples: our state-of-the-art UHPLC-HRMS system offers outstanding analytical depth and accuracy. Analyses are performed on an Agilent 1290 Infinity® LC system coupled with a maXisII™ ESI-QTOF mass spectrometer from Bruker Daltonics.

 

Microfractionation and dereplication

Our platform enables the separation of complex mixtures on a microlitre scale, either in 384-well or 96-well formats. High-resolution masses and fragmentations are also recorded simultaneously. This allows one or more molecular formulas to be assigned to individual active fractions, which is a basic requirement for efficient data evaluation.

Depending on your needs, you can perform your own bioassays, after which we analyse the MS and MS/MS data of the active fractions for consistency with known substances. Alternatively, you can use the natural product research platform, which combines bioassays and MS data in-house and specialises in the dereplication of known natural products.

 

Isolation and structural elucidation

For structural elucidation, we isolate 1 to 5 mg of high-purity substance for you using various chromatography systems (flash, HPLC, UHPLC). The subsequent NMR measurement at 700 MHz (Bruker) provides precise structural information, which is evaluated by our experienced experts.

We can also purify proteins using biocompatible chromatography.