Genome editing of plants using laser-induced shock waves

Research project - ASTORIA

Motivation and problem

Agriculture is undergoing a major transformation process in which economic, ecological, and social interests must be reconciled. Modern plant breeding plays a key role in achieving the political goals for agriculture outlined in the EU member states' Green Deal, Farm to Fork Strategy, and Common Agricultural Policy. The steady increase in the world's population, limited cultivation area, scarcity of water resources, extreme weather events exacerbated by climate change, and the spread of pathogens require the development of high-yielding, nutritious, and resilient crops.  The ASTORIA project aims to address these challenges and develop a precise, fast, and efficient plant breeding method to increase sustainability in agriculture.

Objective and solution

© Fraunhofer IME
Laser-induced shock waves are used in the project to induce genetic changes in crops. The method can be used to induce targeted mutations through genome editing or to introduce recombinant DNA into plant cells. The method has been established using tobacco as a model plant and will be transferred to crops as part of the project in order to tap into the economic potential of the application.

The main objective of the project is to validate and further develop a patent-pending technology for laser-induced genome editing, which is intended to facilitate plant breeding. The approach involves developing a process that uses shock waves from cavitation bubbles to efficiently modify the genetic material of plant cells. The process has already been demonstrated using tobacco plants (Nicotiana tabacum) as an example. The work is being carried out by Fraunhofer IME, with the aim of transferring the technology to various economically relevant crops and identifying potential licensees. The project results should enable the development of new, adaptable plant varieties, which will benefit both agriculture and society by contributing to food security and climate protection.

Project profile

Project title ASTORIA: Laser-induced shock waves for plant transformation
duration 03/2024 – 08/2025
Promotion

Call for projects: “NRW Patent Validation” Funding from state funds and the European Regional Development Fund (ERDF)

Funding approx. 157,000 euros
Project leader Dr. Andreas Schiermeyer
objectives
  • Validation of patent applications for transfer to selected crops
  • Initiation of cooperation for the second funding phase to develop the economic potential of this technology

Are you interested in this topic? Please contact us!

Andreas Schiermeyer

Contact Press / Media

Dr. Andreas Schiermeyer

Fraunhofer Institute for Molecular Biology and Applied Ecology IME
Forckenbeckstr. 6
52074 Aachen

Phone +49 241 6085-201

Stefano Di Fiore

Contact Press / Media

Stefano Di Fiore

Fraunhofer Institute for Molecular Biology and Applied Ecology IME
Forckenbeckstr. 6
52074 Aachen

Phone +49 241 6085-146

Nicole Raven

Contact Press / Media

Dr. Nicole Raven

Fraunhofer Institute for Molecular Biology and Applied Ecology IME
Forckenbeckstr. 6
52074 Aachen

Phone +49 241 6085-197