Fraunhofer Institute for Molecular Biology and Applied Ecology IMEThe OECD TG 317 describes a standardized method for determining the bioaccumulation of chemicals in terrestrial oligochaetes such as earthworms. The test includes an uptake and an elimination phase, during which the concentration of the substance in organisms and soil is measured. Key parameters include the bioaccumulation factor (BAF) as well as uptake and elimination rates. The method is particularly relevant for persistent, lipophilic substances. It contributes to the risk assessment of chemicals, especially with regard to secondary poisoning in terrestrial ecosystem food chains.
Fraunhofer IME provides a comprehensive “full-service” offering for OECD TG 317 studies – from planning and execution to regulatory-ready data evaluation – with a strong focus on quality, standardization, and analytical precision.
Our services include:
Study design according OECD TG 317
Conduct of uptake (up to 21 days) and elimination phases (a further 21 days) under controlled laboratory conditions. Fraunhofer IME performs full bioaccumulation studies with earthworms (e.g., Eisenia andreii).