Protein Production Services

Fraunhofer IME has a 15-year track record in the production of a large number of recombinant proteins from a wide range of expression systems (see below).
An array of 9 stirred-tank bioreactors ranging from 1 to 30 L working volume are available for process development and non-GMP protein production. Matching downstream processing equipment (cell separation, filtration, chromatography) is available.
The list of expression systems routinely cultivated for the production of recombinant proteins includes:

Escherichia coli

Pichia pastoris

Hansenula polymorpha

Schizosaccharomyces pombe

Saccharomyces cerevisiae

Nicotiana tabacum (various cultivars)

Oryza sativa (various cultivars)

CHO cells

Hybridoma cell lines

HeLa cells

HEK 293 cells