This research area comprises the investigation of uptake and metabolism of agrochemicals in crops and farm animals (initially in cultured fish) according to national and international legislation, e.g. EC 1107/2009 as basis for the assessment of consumer risks.
High resolution mass spectroscopy combined with cutting-edge NMR analytics and radiolabelling (14C) allows the determination and identification of unknown metabolites according to GLP.
Bischof I., Köster, J., Segner H., Schlechtriem C.:
Hepatocytes as an in vitro test system to investigate the metabolism of pesticides in farmed fish: comparison between in vivo and in vitro and across species. Comparative Biochemistry and Physiology, Part C 187 (2016) 62–73 (DOI: 10.1016/j.cbpc.2016.05.003)
Schlechtriem, C., Pucher, J., Michalski, B.:
Dietary burden calculations relating to fish metabolism studies. Journal of the Science of Food and Agriculture 96 (5) (2016) 1415–1419
(DOI: 10.1002/jsfa.7607)
Schlechtriem, C., Bischof, I., Atorf, C., Bergendahl, E., Seymour, P., Whalley, P.:
Development of a regulatory testing procedure to study the metabolism of pesticides in farmed fish. Pest Management Science 72 (2016), 362-270 (DOI: 10.1002/ps.4007)
Goeritz, I., Atorf, C., Whalley, P., Seymour, P., Klein, M., Schlechtriem, C.:
Investigation into feed preparation for regulatory fish metabolism studies. Journal of the Science of Food and Agriculture 94 (2014) No. 3: 438–444 (DOI: 10.1002/jsfa.6262)