This research area comprises the investigation of uptake and metabolism of agrochemicals in crops and farm animals (initially in cultured fish) according to national and international legislation, e.g. EC 1107/2009 as basis for the assessment of consumer risks.
High resolution mass spectroscopy combined with cutting-edge NMR analytics and radiolabelling (14C) allows the determination and identification of unknown metabolites according to GLP.
Bischof I., Köster, J., Segner H., Schlechtriem C.:
Hepatocytes as an in vitro test system to investigate the metabolism of pesticides in farmed fish: comparison between in vivo and in vitro and across species. Comparative Biochemistry and Physiology, Part C 187 (2016) 62–73 (DOI: 10.1016/j.cbpc.2016.05.003)
Schlechtriem, C., Pucher, J., Michalski, B.:
Dietary burden calculations relating to fish metabolism studies. Journal of the Science of Food and Agriculture 96 (5) (2016) 1415–1419
Schlechtriem, C., Bischof, I., Atorf, C., Bergendahl, E., Seymour, P., Whalley, P.:
Development of a regulatory testing procedure to study the metabolism of pesticides in farmed fish. Pest Management Science 72 (2016), 362-270 (DOI: 10.1002/ps.4007)
Goeritz, I., Atorf, C., Whalley, P., Seymour, P., Klein, M., Schlechtriem, C.:
Investigation into feed preparation for regulatory fish metabolism studies. Journal of the Science of Food and Agriculture 94 (2014) No. 3: 438–444 (DOI: 10.1002/jsfa.6262)